Literature DB >> 2976081

Imaging of cerebral blood flow markers in Huntington's disease using single photon emission computed tomography.

I C Reid1, J A Besson, P V Best, P F Sharp, H G Gemmell, F W Smith.   

Abstract

Single photon emission computed tomography (SPECT) imaging of six Huntington's disease patients revealed a striking reduction in regional uptake of cerebral blood flow markers in vivo. Similar changes were found in one patient with "early stage" disease. The findings are compared with parallel magnetic resonance imaging (MRI) studies, and in one case, results of postmortem examination.

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Year:  1988        PMID： 2976081      PMCID： PMC1032912          DOI： 10.1136/jnnp.51.10.1264

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  13 in total

1.  Local cerebral glucose utilization in symptomatic and presymptomatic Huntington's disease.

Authors:  D E Kuhl; C H Markham; E J Metter; W H Riege; M E Phelps; J C Mazziotta
Journal:  Res Publ Assoc Res Nerv Ment Dis       Date:  1985

2.  Focal physiological uncoupling of cerebral blood flow and oxidative metabolism during somatosensory stimulation in human subjects.

Authors:  P T Fox; M E Raichle
Journal:  Proc Natl Acad Sci U S A       Date:  1986-02       Impact factor: 11.205

3.  Magnetic resonance imaging in Huntington disease.

Authors:  J T Simmons; B Pastakia; T N Chase; C W Shults
Journal:  AJNR Am J Neuroradiol       Date:  1986 Jan-Feb       Impact factor: 3.825

4.  Pneumoencephalographic findings in Huntington's chorea.

Authors:  I Gath; B Vinje
Journal:  Neurology       Date:  1968-10       Impact factor: 9.910

5.  A polymorphic DNA marker genetically linked to Huntington's disease.

Authors:  J F Gusella; N S Wexler; P M Conneally; S L Naylor; M A Anderson; R E Tanzi; P C Watkins; K Ottina; M R Wallace; A Y Sakaguchi
Journal:  Nature       Date:  1983 Nov 17-23       Impact factor: 49.962

6.  Bicaudate diameter--the most specific and simple CT parameter in the diagnosis of Huntington's disease.

Authors:  T Stober; W Wussow; K Schimrigk
Journal:  Neuroradiology       Date:  1984       Impact factor: 2.804

Review 7.  Radioactive oxygen-15 in the study of cerebral blood flow, blood volume, and oxygen metabolism.

Authors:  M M Ter-Pogossian; P Herscovitch
Journal:  Semin Nucl Med       Date:  1985-10       Impact factor: 4.446

8.  Differential diagnosis in dementia using the cerebral blood flow agent 99mTc HM-PAO: a SPECT study.

Authors:  H G Gemmell; P F Sharp; J A Besson; J R Crawford; K P Ebmeier; J Davidson; F W Smith
Journal:  J Comput Assist Tomogr       Date:  1987 May-Jun       Impact factor: 1.826

9.  Cerebral metabolism and atrophy in Huntington's disease determined by 18FDG and computed tomographic scan.

Authors:  D E Kuhl; M E Phelps; C H Markham; E J Metter; W H Riege; J Winter
Journal:  Ann Neurol       Date:  1982-11       Impact factor: 10.422

10.  Morphometric studies of the neuropathological changes in choreatic diseases.

Authors:  H Lange; G Thörner; A Hopf; K F Schröder
Journal:  J Neurol Sci       Date:  1976-08       Impact factor: 3.181
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  1 in total

1.  SPECT, CT and MRI in a Turkish family with Huntington's disease.

Authors:  R P Bruyn; G Hageman; J A Geelen; F A van der Weel; A R Rozeboom; F Barkhof; P Scheltens
Journal:  Neuroradiology       Date:  1993       Impact factor: 2.804
  1 in total

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