Literature DB >> 29759126

Primary Care Vasculitis: Polymyalgia Rheumatica and Giant Cell Arteritis.

Mathilde H Pioro1.   

Abstract

Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are related inflammatory diseases of adults aged 50 years or older. The diagnosis of PMR is based on morning stiffness, proximal shoulder and pelvic girdle pain, and functional impairment. GCA is characterized by headache, jaw claudication, and visual disturbances. Constitutional symptoms and elevated inflammatory markers are common to both conditions. Temporal artery biopsy remains the gold standard for diagnosis of GCA. Glucocorticoids are the cornerstone of therapy, with tapering regimens individualized to the patient. Prompt diagnosis and treatment are essential to avert vision loss in GCA. Tocilizumab increases remission rates in GCA.
Copyright © 2018 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Corticosteroids; Giant cell arteritis; Polymyalgia rheumatica; Temporal artery biopsy; Tocilizumab

Mesh:

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Year:  2018        PMID: 29759126     DOI: 10.1016/j.pop.2018.02.007

Source DB:  PubMed          Journal:  Prim Care        ISSN: 0095-4543            Impact factor:   2.907


  1 in total

1.  Corticosteroid Usage in Giant Cell Arteritis.

Authors:  Amritha Kanakamedala; Mariam Hussain; Ashwini Kini; Bayan Al Othman; Andrew G Lee
Journal:  Neuroophthalmology       Date:  2020-07-16
  1 in total

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