Literature DB >> 29756452

γ-Carboline Synthesis by Heterocyclization of TosMIC Derivatives.

Sara Gutiérrez1, David Sucunza1, Juan J Vaquero1.   

Abstract

A new method for the synthesis of γ-carbolines by a heterocyclization that involves α-indol-2-ylmethyl TosMIC derivatives and different electrophiles has been developed. This methodology has been successfully applied to the synthesis of several highly substituted γ-carbolines.

Entities:  

Year:  2018        PMID： 29756452     DOI： 10.1021/acs.joc.8b00906

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  1 in total

1.  Synthesis of 1-indolyl-3,5,8-substituted γ-carbolines: one-pot solvent-free protocol and biological evaluation.

Authors:  Premansh Dudhe; Mena Asha Krishnan; Kratika Yadav; Diptendu Roy; Krishnan Venkatasubbaiah; Biswarup Pathak; Venkatesh Chelvam
Journal:  Beilstein J Org Chem       Date:  2021-06-17       Impact factor: 2.883
  1 in total

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