Literature DB >> 29756063

The Carrico index is the parameter that guides the requirement of oxygen in the postoperative period in patients undergoing head and neck surgery under general anaesthesia: a cross-sectional study.

Parnandi Bhaskar Rao1, Manaswini Mangaraj2, Preetam Mahajan3, Swagata Tripathy1, Neha Singh1, Thenmozhi Mani4, Sukdev Nayak1.   

Abstract

BACKGROUND & AIMS: Altered lung function and consequent decrease in oxygenation has been linked to the duration of anaesthesia. This necessitates oxygen monitoring and supplementation in the perioperative period. But, evidence is lacking regarding the parameter that guides best the oxygen supplementation in the postoperative period and the parameter that correlates best with the duration of anaesthesia.
METHODS: Adult patients scheduled for head & neck surgery under general anaesthesia were recruited. Two radial arterial blood samples one at pre-induction and the other at one hour after extubation were obtained. Primary outcome measures were partial pressure of oxygen (PaO2), saturation (SpO2), arterial oxygen content (CaO2) and Carrico index (PaO2/FiO2) and their relation with duration of anaesthesia.
RESULTS: Data from 112 patients showed a hypoxaemia incidence of 11.6%. We observed a drop in the mean CaO2 and haemoglobin concentration but a rise in the mean PaO2 at recovery. The mean PaO2/FiO2 deteriorated by 225.65 ± 72.46 (95% CI 367.66, 83.64, p = 0.000) at recovery and there was a significant correlation (r = 0.2, p = 0.03) between duration of anaesthesia and decrease in PaO2/FiO2 at recovery with a regression coefficient of 0.27 (95% CI 0.02, 0.50).
CONCLUSIONS: The Carrico index was proven to be the best parameter which needs to be monitored perioperatively to detect the alteration in the gaseous exchange in patients undergoing general anaesthesia for head and neck surgery. There is a positive correlation between the decrease in the Carrico index and the duration of anaesthesia especially when it is prolonged beyond 150 minutes.

Entities:  

Keywords:  Carrico index; anaesthesia; duration; head and neck; hypoxaemia; surgery

Year:  2018        PMID: 29756063      PMCID: PMC5931183          DOI: 10.21454/rjaic.7518.251.crc

Source DB:  PubMed          Journal:  Rom J Anaesth Intensive Care        ISSN: 2392-7518


  19 in total

1.  Hypoxaemia after general anaesthesia.

Authors:  J F NUNN; J P PAYNE
Journal:  Lancet       Date:  1962-09-29       Impact factor: 79.321

2.  PERISCOPE study: predicting post-operative pulmonary complications in Europe.

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3.  The incidence of hypoxemia during surgery: evidence from two institutions.

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4.  Incidence of and risk factors for pulmonary complications after nonthoracic surgery.

Authors:  Finlay A McAlister; Kimberly Bertsch; Jeremy Man; John Bradley; Michael Jacka
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5.  Predictive Factors Involved in Development of Postoperative Pulmonary Complications.

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Authors:  M D Daley; P H Norman; M E Colmenares; A N Sandler
Journal:  Can J Anaesth       Date:  1991-09       Impact factor: 5.063

7.  Early postoperative arterial oxygen desaturation. Determining factors and response to oxygen therapy.

Authors:  J Canet; M Ricos; F Vidal
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Review 8.  Mechanisms of hypoxemia.

Authors:  Malay Sarkar; N Niranjan; P K Banyal
Journal:  Lung India       Date:  2017 Jan-Feb

9.  Perioperative hypoxemia is common with horizontal positioning during general anesthesia and is associated with major adverse outcomes: a retrospective study of consecutive patients.

Authors:  C Michael Dunham; Barbara M Hileman; Amy E Hutchinson; Elisha A Chance; Gregory S Huang
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Review 10.  Relating oxygen partial pressure, saturation and content: the haemoglobin-oxygen dissociation curve.

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