| Literature DB >> 2975583 |
H T Salem1, M Salah, M Y Aly, A I Thabet, M M Shaaban, M F Fathalla.
Abstract
The present work was a randomized comparative study of two injectable progestogen-only contraceptives. The first group (200 subjects) received 150 mg of depotmedroxyprogesterone acetate (Depoprovera) every 84 +/- 7 days and the second (200 subjects) received 200 mg of norethisterone enanthate (Noristerat) every 56 +/- 7 days. Acceptors of injectable contraceptives in Assiut, Egypt, were mainly women looking for fertility termination. Menstrual disruption was the main side effect among both treatment groups. Amenorrhoea was the commonest menstrual complaint and was the main reason for discontinuation in both groups. Only one pregnancy occurred during NET-EN use; two more pregnancies occurred, one in each of the two groups but there were indications that conception preceded the first injection. Menstrual irregularities were generally more frequent with DMPA users. However, DMPA had better one-year continuation rates than NET-EN (68.8 +/- 3.5 and 57.1 +/- 3.6 per 100 women, respectively).Entities:
Keywords: Africa; Amenorrhea; Arab Countries; Biology; Comparative Studies; Contraception; Contraception Continuation; Contraceptive Agents; Contraceptive Agents, Female; Contraceptive Agents, Progestin--administraction and dosage; Contraceptive Agents, Progestin--side effects; Contraceptive Agents--administraction and dosage; Contraceptive Agents--side effects; Contraceptive Methods--administraction and dosage; Contraceptive Usage; Demographic Factors; Developing Countries; Diseases; Egypt; Endocrine System; Family Planning; Fertility; Fertility Measurements; Genital Effects, Female; Genitalia; Genitalia, Female; Hormones; Incidence; Injectables--administraction and dosage; Measurement; Mediterranean Countries; Medroxyprogesterone Acetate--administraction and dosage; Medroxyprogesterone Acetate--side effects; Menstruation Disorders; Norethindrone Enanthate--administraction and dosage; Norethindrone--administraction and dosage; Northern Africa; Physiology; Population; Population Dynamics; Pregnancy Rate; Reproductive Control Agents; Research Methodology; Studies; Urogenital Effects; Urogenital System
Mesh：
Substances：
Year: 1988 PMID： 2975583 DOI： 10.1016/0010-7824(88)90051-0
Source DB: PubMed Journal: Contraception ISSN： 0010-7824 Impact factor: 3.375