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Literature DB >> 29753613

Atherosclerosis Is an Epigenetic Disease.

Suowen Xu¹, Jaroslav Pelisek², Zheng Gen Jin³.

Abstract

Atherosclerosis is a chronic inflammatory and lipid-depository disease that eventually leads to acute cardiovascular events. Emerging evidence supports that epigenetic processes such as DNA methylation, histone modification, and noncoding RNAs play an important role in plaque progression and vulnerability, highlighting the therapeutic potential of epigenetic drugs in cardiovascular therapeutics.

Entities: Chemical Disease Gene Species

Keywords: DNA methylation; atherosclerosis; epigenetics; histone modification; therapeutics

Mesh：

Substances：

Year: 2018 PMID： 29753613 PMCID： PMC7202861 DOI： 10.1016/j.tem.2018.04.007

Source DB: PubMed Journal: Trends Endocrinol Metab ISSN： 1043-2760 Impact factor: 12.015

21 in total

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Authors: Roby Joehanes; Allan C Just; Riccardo E Marioni; Luke C Pilling; Lindsay M Reynolds; Pooja R Mandaviya; Weihua Guan; Tao Xu; Cathy E Elks; Stella Aslibekyan; Hortensia Moreno-Macias; Jennifer A Smith; Jennifer A Brody; Radhika Dhingra; Paul Yousefi; James S Pankow; Sonja Kunze; Sonia H Shah; Allan F McRae; Kurt Lohman; Jin Sha; Devin M Absher; Luigi Ferrucci; Wei Zhao; Ellen W Demerath; Jan Bressler; Megan L Grove; Tianxiao Huan; Chunyu Liu; Michael M Mendelson; Chen Yao; Douglas P Kiel; Annette Peters; Rui Wang-Sattler; Peter M Visscher; Naomi R Wray; John M Starr; Jingzhong Ding; Carlos J Rodriguez; Nicholas J Wareham; Marguerite R Irvin; Degui Zhi; Myrto Barrdahl; Paolo Vineis; Srikant Ambatipudi; André G Uitterlinden; Albert Hofman; Joel Schwartz; Elena Colicino; Lifang Hou; Pantel S Vokonas; Dena G Hernandez; Andrew B Singleton; Stefania Bandinelli; Stephen T Turner; Erin B Ware; Alicia K Smith; Torsten Klengel; Elisabeth B Binder; Bruce M Psaty; Kent D Taylor; Sina A Gharib; Brenton R Swenson; Liming Liang; Dawn L DeMeo; George T O'Connor; Zdenko Herceg; Kerry J Ressler; Karen N Conneely; Nona Sotoodehnia; Sharon L R Kardia; David Melzer; Andrea A Baccarelli; Joyce B J van Meurs; Isabelle Romieu; Donna K Arnett; Ken K Ong; Yongmei Liu; Melanie Waldenberger; Ian J Deary; Myriam Fornage; Daniel Levy; Stephanie J London
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Authors: Juan Peng; Qin Yang; A-Fang Li; Rong-Qing Li; Zuo Wang; Lu-Shan Liu; Zhong Ren; Xi-Long Zheng; Xiao-Qing Tang; Guo-Hua Li; Zhi-Han Tang; Zhi-Sheng Jiang; Dang-Heng Wei
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40 in total

Review 1. Targeting Mechanosensitive Transcription Factors in Atherosclerosis.

Authors: Niu Niu; Suowen Xu; Yanni Xu; Peter J Little; Zheng-Gen Jin
Journal: Trends Pharmacol Sci Date: 2019-02-28 Impact factor: 14.819

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Authors: Suowen Xu; Danielle Kamato; Peter J Little; Shinichi Nakagawa; Jaroslav Pelisek; Zheng Gen Jin
Journal: Pharmacol Ther Date: 2018-11-13 Impact factor: 12.310

Review 3. Relationship between protein arginine methyltransferase and cardiovascular disease (Review).

Authors: Sisi Zheng; Congcong Zeng; Ailing Huang; Fuqi Huang; Anna Meng; Zhuan Wu; Shouhong Zhou
Journal: Biomed Rep Date: 2022-09-16

4. Targeting epigenetic modifiers to reprogramme macrophages in non-resolving inflammation-driven atherosclerosis.

Authors: Fengyan Jin; Jian Li; Jianfeng Guo; Thorsten R Doeppner; Dirk M Hermann; Gang Yao; Yun Dai
Journal: Eur Heart J Open Date: 2021-08-17

Review 5. Relationships among smoking, oxidative stress, inflammation, macromolecular damage, and cancer.

Authors: Andrew W Caliri; Stella Tommasi; Ahmad Besaratinia
Journal: Mutat Res Rev Mutat Res Date: 2021-01-11 Impact factor: 5.657

6. Investigation the Role of Autophagy in Non-Small Cell Lung Cancer.

Authors: Minoo Pargol; Shima Zare Karizi; Masoumeh Akbari; Bahareh Nourmohammadi; Mohammad Behgam Shadmehr; Morteza Karimipoor; Shohreh Zare Karizi
Journal: Asian Pac J Cancer Prev Date: 2021-03-01

7. CHOP Increases TRIB3-Dependent miR-208 Expression to Potentiate Vascular Smooth Muscle Cell Proliferation and Migration by Downregulating TIMP3 in Atherosclerosis.

Authors: Rui Chen; Yan Zhang; Chunyan Zhao
Journal: Cardiovasc Drugs Ther Date: 2021-04-15 Impact factor: 3.947