| Literature DB >> 29750378 |
R Aleyda Garza-Sanchez1, Tuhin Patra1, Adrian Tlahuext-Aca1, Felix Strieth-Kalthoff1, Frank Glorius1.
Abstract
Herein, we report a novel strategy for the activation of DMSO to act as a versatile alkylating agent in heteroarene C-H functionalization. This direct, simple, and mild switch between methylation/trideuteromethylation and methylthiomethylation of heteroarenes was achieved under reagent-controlled photoredox catalysis conditions. The proposed mechanism is supported by both experimental and computational studies.Entities:
Keywords: C−H functionalization; heteroarenes; methylation; methylthiomethylation; photoredox catalysis
Year: 2018 PMID： 29750378 DOI： 10.1002/chem.201802352
Source DB: PubMed Journal: Chemistry ISSN： 0947-6539 Impact factor: 5.236