Zehra Karacaer1, Selma Tosun2, Ayşe Batırel3, Suzan Şahin3, İrem Altaş2, Serhat Uysal4, Serpil Erol5, Nurgül Ceran5, Ayşe Albayrak6, İlknur Esen Yıldız7, Uğur Kostakoğlu7, Fatma Kaçar8, Nuretdin Kuzhan9, Ayten Kadanalı10, Gül Karagöz10, Ercan Yenilmez11, Derya Bayırlı Turan12, Arzu Altunçekiç Yıldırım13, Funda Koçak14, Rıza Aytaç Çetinkaya11, Mehmet Parlak6, Özlem Aydın15, Pınar Ergen15, Gül Durmuş16, Türkkan Öztürk Kaygusuz17, Özgur Dağlı16, Canan Demir16, Fatma Yılmaz Karadağ15. 1. Department of Infectious Diseases and Clinical Microbiology, Gülhane Training and Research Hospital, Ankara, Turkey. 2. Department of Infectious Diseases and Clinical Microbiology, Bozyaka Training and Research Hospital, İzmir, Turkey. 3. Department of Infectious Diseases and Clinical Microbiology, Kartal Dr. Lütfi Kirdar Education and Research Hospital, İstanbul, Turkey. 4. Department of Infectious Diseases and Clinical Microbiology, Buca Seyfi Demirsoy State Hospital, İzmir, Turkey. 5. Department of Infectious Diseases and Clinical Microbiology, Haydarpaşa Numune Training and Research Hospital, İstanbul, Turkey. 6. Department of Infectious Diseases and Clinical Microbiology, Atatürk University School of Medicine, Erzurum, Turkey. 7. Department of Infectious Diseases and Clinical Microbiology, Rize University School of Medicine, Rize, Turkey. 8. Department of Infectious Diseases and Clinical Microbiology, Konya Training and Research Hospital, Konya, Turkey. 9. Department of Infectious Diseases and Clinical Microbiology, Sütçü İmam University School of Medicine, Kahramanmaraş, Turkey. 10. Department of Infectious Diseases and Clinical Microbiology, Ümraniye Training and Research Hospital, İstanbul, Turkey. 11. Department of Infectious Diseases and Clinical Microbiology, Haydarpaşa Sultan Abdulhamid Training and Research Hospital, İstanbul, Turkey. 12. Department of Infectious Diseases and Clinical Microbiology, Yeni Yüzyıl University School of Medicine, İstanbul, Turkey. 13. Department of Infectious Diseases and Clinical Microbiology, Ordu University School of Medicine, Ordu, Turkey. 14. Department of Infectious Diseases and Clinical Microbiology, Başakşehir State Hospital, İstanbul, Turkey. 15. Department of Infectious Diseases and Clinical Microbiology, İstanbul Medeniyet University, Göztepe Training and Research Hospital, İstanbul, Turkey. 16. Department of Infectious Diseases and Clinical Microbiology, Bursa Yüksek İhtisas Training and Research Hospital, İstanbul, Turkey. 17. Department of Infectious Diseases and Clinical Microbiology, Elazığ Training and Research Hospital, Elazığ, Turkey.
Abstract
BACKGROUND/AIMS: The present study aimed to determine the changes in the epidemiology of hepatitis in recent years in an adult Turkish population. MATERIALS AND METHODS: Overall, 852 patients with acute viral hepatitis from 17 centers were included in this study. Their sociodemographic characteristics, clinical courses, treatments, and laboratory findings were retrospectively analyzed. RESULTS: The most commonly found microorganisms were the hepatitis B virus (55.2%) and hepatitis A virus (37.6%), and the types of acute viral hepatitis differed significantly according to the age group (p≤0.001). The most frequently reported symptom was fatigue (73.7%), and the most common complications were cholecystitis (0.4%) and fulminant hepatitis (0.4%). The median hospital stay was 9 days (range 1-373). In total, 40.8% patients with acute hepatitis B virus developed immunity. CONCLUSION: In Turkey, there are significantly large adolescent and adult populations susceptible to acute viral hepatitis. Therefore, larger vaccination programs covering these age groups should be implemented.
BACKGROUND/AIMS: The present study aimed to determine the changes in the epidemiology of hepatitis in recent years in an adult Turkish population. MATERIALS AND METHODS: Overall, 852 patients with acute viral hepatitis from 17 centers were included in this study. Their sociodemographic characteristics, clinical courses, treatments, and laboratory findings were retrospectively analyzed. RESULTS: The most commonly found microorganisms were the hepatitis B virus (55.2%) and hepatitis A virus (37.6%), and the types of acute viral hepatitis differed significantly according to the age group (p≤0.001). The most frequently reported symptom was fatigue (73.7%), and the most common complications were cholecystitis (0.4%) and fulminant hepatitis (0.4%). The median hospital stay was 9 days (range 1-373). In total, 40.8% patients with acute hepatitis B virus developed immunity. CONCLUSION: In Turkey, there are significantly large adolescent and adult populations susceptible to acute viral hepatitis. Therefore, larger vaccination programs covering these age groups should be implemented.
Authors: Selim Badur; Serdar Öztürk; Alev Ozakay; Mansour Khalaf; Debasish Saha; Pierre Van Damme Journal: Hum Vaccin Immunother Date: 2021-07-02 Impact factor: 4.526