Literature DB >> 29748016

Lorlatinib - Induced pulmonary arterial hypertension.

Alexandre Chabrol1, Marie Mayenga2, Abdul Momen Hamid2, Sylvie Friard2, Hélène Salvator3, Hélèe Doubre2, Séverine Fraboulet2, Anne-Cécile Metivier2, Emilie Catherinot2, Elisabeth Rivaud2, Marie Camille Chaumais4, David Montani5, Louis Jean Couderc3, Colas Tcherakian6.   

Abstract

We report here the first cases, to our knowledge, of pulmonary arterial hypertension induced by lorlatinib. It s the first time that a tyrosine kinase inhibitor for lung cancer is associated with pulmonary arteriel hypertension.
Copyright © 2018 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  ALK rearrangement; Lorlatinib; Lung cancer; Pulmonary hypertension; Tyrosine kinase inhibitor

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Year:  2018        PMID: 29748016     DOI: 10.1016/j.lungcan.2018.03.023

Source DB:  PubMed          Journal:  Lung Cancer        ISSN: 0169-5002            Impact factor:   5.705


  1 in total

1.  Pharmacovigilance in a rare disease: example of the VIGIAPATH program in pulmonary arterial hypertension.

Authors:  Marie-Camille Chaumais; Caroline O'Connell; Laurent Savale; Christophe Guignabert; Frédéric Perros; Xavier Jaïs; Olivier Sitbon; Marc Humbert; David Montani
Journal:  Int J Clin Pharm       Date:  2018-08-13
  1 in total

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