Rafael de Oliveira Alvim1, Divanei Zaniqueli2, Felipe Silva Neves3, Virgilia Oliveira Pani4, Caroline Resende Martins4, Marcos Alves de Souza Peçanha4, Míriam Carmo Rodrigues Barbosa4, Eliane Rodrigues de Faria5, José Geraldo Mill6. 1. Universidade Federal do Espírito Santo (UFES), Clínica de Investigação Cardiovascular, Vitória, ES, Brazil; Universidade Federal do Espírito Santo (UFES), Programa de Pós-Graduação em Saúde Coletiva, Vitória, ES, Brazil. Electronic address: r.alvim@hotmail.com. 2. Universidade Federal do Espírito Santo (UFES), Clínica de Investigação Cardiovascular, Vitória, ES, Brazil. 3. Universidade Federal de Juiz de Fora (UFJF), Instituto de Ciências Biológicas, Departamento de Nutrição, Juiz de Fora, MG, Brazil. 4. Universidade Federal do Espírito Santo (UFES), Programa de Pós-Graduação em Nutrição e Saúde, Vitória, ES, Brazil. 5. Universidade Federal de Juiz de Fora (UFJF), Instituto de Ciências Biológicas, Departamento de Nutrição, Juiz de Fora, MG, Brazil; Universidade Federal do Espírito Santo (UFES), Programa de Pós-Graduação em Nutrição e Saúde, Vitória, ES, Brazil. 6. Universidade Federal do Espírito Santo (UFES), Clínica de Investigação Cardiovascular, Vitória, ES, Brazil; Universidade Federal do Espírito Santo (UFES), Programa de Pós-Graduação em Saúde Coletiva, Vitória, ES, Brazil.
Abstract
OBJECTIVE: Given the importance of incorporating simple and low-cost tools into the pediatric clinical setting to provide screening for insulin resistance, the present study sought to investigate whether waist-to-height ratio is comparable to biochemical markers for the discrimination of insulin resistance in children and adolescents. METHODS: This cross-sectional study involved students from nine public schools. In total, 296 children and adolescents of both sexes, aged 8-14 years, composed the sample. Waist-to-height ratio, triglycerides/glucose index, and triglycerides-to-HDL-C ratio were determined according to standard protocols. Insulin resistance was defined as homeostatic model assessment for insulin resistance with cut-off point ≥ 3.16. RESULTS: Age, body mass index, frequency of overweight, waist circumference, waist-to-height ratio, insulin, glucose, homeostatic model assessment for insulin resistance, triglycerides, triglycerides/glucose index, and triglycerides-to-HDL-C were higher among insulin resistant boys and girls. Moderate correlation of all indicators (waist-to-height ratio, triglycerides/glucose index, and triglycerides-to-HDL-C ratio) with homeostatic model assessment for insulin resistance was observed for both sexes. The areas under the receiver operational characteristic curves ware similar between waist-to-height ratio and biochemical markers. CONCLUSION: The indicators provided similar discriminatory power for insulin resistance. However, taking into account the cost-benefit ratio, we suggest that waist-to-height ratio may be a useful tool to provide screening for insulin resistance in pediatric populations.
OBJECTIVE: Given the importance of incorporating simple and low-cost tools into the pediatric clinical setting to provide screening for insulin resistance, the present study sought to investigate whether waist-to-height ratio is comparable to biochemical markers for the discrimination of insulin resistance in children and adolescents. METHODS: This cross-sectional study involved students from nine public schools. In total, 296 children and adolescents of both sexes, aged 8-14 years, composed the sample. Waist-to-height ratio, triglycerides/glucose index, and triglycerides-to-HDL-C ratio were determined according to standard protocols. Insulin resistance was defined as homeostatic model assessment for insulin resistance with cut-off point ≥ 3.16. RESULTS: Age, body mass index, frequency of overweight, waist circumference, waist-to-height ratio, insulin, glucose, homeostatic model assessment for insulin resistance, triglycerides, triglycerides/glucose index, and triglycerides-to-HDL-C were higher among insulin resistant boys and girls. Moderate correlation of all indicators (waist-to-height ratio, triglycerides/glucose index, and triglycerides-to-HDL-C ratio) with homeostatic model assessment for insulin resistance was observed for both sexes. The areas under the receiver operational characteristic curves ware similar between waist-to-height ratio and biochemical markers. CONCLUSION: The indicators provided similar discriminatory power for insulin resistance. However, taking into account the cost-benefit ratio, we suggest that waist-to-height ratio may be a useful tool to provide screening for insulin resistance in pediatric populations.
Authors: Jana Jurkovičová; Katarína Hirošová; Diana Vondrová; Martin Samohýl; Zuzana Štefániková; Alexandra Filová; Ivana Kachútová; Jana Babjaková; Ľubica Argalášová Journal: Int J Environ Res Public Health Date: 2021-01-21 Impact factor: 3.390
Authors: Ahmad Kamil Nur Zati Iwani; Muhammad Yazid Jalaludin; Ruziana Mona Wan Mohd Zin; Md Zain Fuziah; Janet Yeow Hua Hong; Yahya Abqariyah; Abdul Halim Mokhtar; Wan Nazaimoon Wan Mohamud Journal: Int J Endocrinol Date: 2019-12-01 Impact factor: 3.257