Literature DB >> 29746611

Adult Human Hippocampus: No New Neurons in Sight.

Jon I Arellano1, Brian Harding2, Jean-Leon Thomas3,4.   

Abstract

In this issue of Cerebral Cortex, Cipriani et al. are following up on the recent report of Sorrels et al. to add novel immunohistological observations indicating that, unlike rodents, adult and aging humans do not acquire new neurons in the hippocampus. The common finding emerging from these 2 different, but almost simultaneous studies is highly significant because the dentate gyrus of the hippocampus was, until recently, considered as the only structure in the human brain that may continue neurogenesis throughout the full life span.

Entities:  

Mesh:

Year:  2018        PMID: 29746611     DOI: 10.1093/cercor/bhy106

Source DB:  PubMed          Journal:  Cereb Cortex        ISSN: 1047-3211            Impact factor:   5.357


  6 in total

Review 1.  A balanced evaluation of the evidence for adult neurogenesis in humans: implication for neuropsychiatric disorders.

Authors:  Alvaro Duque; Reynold Spector
Journal:  Brain Struct Funct       Date:  2019-07-05       Impact factor: 3.270

Review 2.  An assessment of the existence of adult neurogenesis in humans and value of its rodent models for neuropsychiatric diseases.

Authors:  Alvaro Duque; Jon I Arellano; Pasko Rakic
Journal:  Mol Psychiatry       Date:  2021-10-19       Impact factor: 15.992

3.  Saikosaponin-d impedes hippocampal neurogenesis and causes cognitive deficits by inhibiting the survival of neural stem/progenitor cells via neurotrophin receptor signaling in mice.

Authors:  Tingting Qin; Ziqiao Yuan; Jiayu Yu; Xinxin Fu; Xueyang Deng; Qiang Fu; Zhanqiang Ma; Shiping Ma
Journal:  Clin Transl Med       Date:  2020-12

Review 4.  Humans and Dolphins: Decline and Fall of Adult Neurogenesis.

Authors:  Roberta Parolisi; Bruno Cozzi; Luca Bonfanti
Journal:  Front Neurosci       Date:  2018-07-20       Impact factor: 4.677

Review 5.  Alzheimer's disease, neural stem cells and neurogenesis: cellular phase at single-cell level.

Authors:  Mehmet Ilyas Cosacak; Prabesh Bhattarai; Caghan Kizil
Journal:  Neural Regen Res       Date:  2020-05       Impact factor: 5.135

6.  Neuron-glia interaction through Serotonin-BDNF-NGFR axis enables regenerative neurogenesis in Alzheimer's model of adult zebrafish brain.

Authors:  Prabesh Bhattarai; Mehmet Ilyas Cosacak; Violeta Mashkaryan; Sevgican Demir; Stanislava Dimitrova Popova; Nambirajan Govindarajan; Kerstin Brandt; Yixin Zhang; Weipang Chang; Konstantinos Ampatzis; Caghan Kizil
Journal:  PLoS Biol       Date:  2020-01-06       Impact factor: 8.029

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.