Literature DB >> 29745320

Honey: An Effective Regenerative Medicine Product in Wound Management.

Simona Martinotti1, Marcela Bucekova2, Juraj Majtan2, Elia Ranzato3.   

Abstract

Honey has successfully been used in the treatment of a broad spectrum of injuries including burns and non-healing wounds. It acts as an antibacterial and anti-biofilm agent with anti/pro-inflammatory properties. However, besides these traditional properties, recent evidence suggests that honey is also an immunomodulator in wound healing and contains several bee and plant-derived components that may speed up wound healing and tissue regeneration process. Identifying their exact mechanism of action allows better understanding of honey healing properties and promotes its wider translation into clinical practice. This review will discuss the physiological basis for the use of honey in wound management, its current clinical uses, as well as the potential role of honey bioactive compounds in dermal regenerative medicine and tissue re-modeling. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Keywords:  Honey; immunomodulator; regenerative medicine; tissue; wound healing; wound repair.

Mesh:

Substances:

Year:  2019        PMID: 29745320     DOI: 10.2174/0929867325666180510141824

Source DB:  PubMed          Journal:  Curr Med Chem        ISSN: 0929-8673            Impact factor:   4.530


  4 in total

1.  Endothelial and Vascular Health: A Tale of Honey, H2O2 and Calcium.

Authors:  Elia Ranzato; Gregorio Bonsignore; Mauro Patrone; Simona Martinotti
Journal:  Cells       Date:  2021-04-30       Impact factor: 6.600

2.  Evaluation of the In Vitro Wound-Healing Activity of Calabrian Honeys.

Authors:  Paolo Governa; Gabriele Carullo; Marco Biagi; Vittoria Rago; Francesca Aiello
Journal:  Antioxidants (Basel)       Date:  2019-02-06

3.  A pilot study investigating the effects of a manuka honey sinus rinse compared to a standard sinus rinse on sino-nasal outcome test scores in cystic fibrosis patients.

Authors:  Aled E L Roberts; Cendl Xanthe; Alison L Hopkins; Owen Bodger; Paul Lewis; Eshwar Mahenthiralingam; Jamie Duckers; Rowena E Jenkins
Journal:  Pilot Feasibility Stud       Date:  2022-09-24

Review 4.  "Green" Biomaterials: The Promising Role of Honey.

Authors:  Gregorio Bonsignore; Mauro Patrone; Simona Martinotti; Elia Ranzato
Journal:  J Funct Biomater       Date:  2021-12-09
  4 in total

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