Literature DB >> 29741103

Recent breakthroughs in metastatic uveal melanoma: a cause for optimism?

Joseph J Sacco1,2, Helen Kalirai1, Jenna Kenyani1, Carlos R Figueiredo1, Judy M Coulson1,3, Sarah E Coupland1,4.   

Abstract

Entities:  

Keywords:  IMCgp100; MEK inhibitors selumetinib; checkpoint inhibitors; immunotherapy; tumor infiltrating lymphocytes; uveal melanoma

Mesh：

Substances：

Year:  2018        PMID： 29741103     DOI： 10.2217/fon-2018-0116

Source DB:  PubMed          Journal:  Future Oncol        ISSN： 1479-6694            Impact factor:   3.404


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  9 in total

1.  Aggressive uveal melanoma displays a high degree of centrosome amplification, opening the door to therapeutic intervention.

Authors:  Dorota Sabat-Pośpiech; Kim Fabian-Kolpanowicz; Helen Kalirai; Natalie Kipling; Sarah E Coupland; Judy M Coulson; Andrew B Fielding
Journal:  J Pathol Clin Res       Date:  2022-04-26

Review 2.  New tools to prevent cancer growth and spread: a 'Clever' approach.

Authors:  Maija Hollmén; Carlos R Figueiredo; Sirpa Jalkanen
Journal:  Br J Cancer       Date:  2020-06-29       Impact factor: 7.640

3.  Expression of immune checkpoint receptors Indoleamine 2,3-dioxygenase and T cell Ig and ITIM domain in metastatic versus nonmetastatic choroidal melanoma.

Authors:  Gustav Stålhammar; Stefan Seregard; Hans E Grossniklaus
Journal:  Cancer Med       Date:  2019-04-16       Impact factor: 4.452

Review 4.  Scientific and clinical implications of genetic and cellular heterogeneity in uveal melanoma.

Authors:  Mark J de Lange; Rogier J Nell; Pieter A van der Velden
Journal:  Mol Biomed       Date:  2021-08-20

5.  Small High-Risk Uveal Melanomas Have a Lower Mortality Rate.

Authors:  Rumana N Hussain; Sarah E Coupland; Helen Kalirai; Azzam F G Taktak; Antonio Eleuteri; Bertil E Damato; Carl Groenewald; Heinrich Heimann
Journal:  Cancers (Basel)       Date:  2021-05-08       Impact factor: 6.639

Review 6.  Clinical Trials in Metastatic Uveal Melanoma: Immunotherapy.

Authors:  Marlana Orloff
Journal:  Ocul Oncol Pathol       Date:  2021-03-31

7.  Loss of BAP1 expression is associated with an immunosuppressive microenvironment in uveal melanoma, with implications for immunotherapy development.

Authors:  Carlos R Figueiredo; Helen Kalirai; Joseph J Sacco; Ricardo A Azevedo; Andrew Duckworth; Joseph R Slupsky; Judy M Coulson; Sarah E Coupland
Journal:  J Pathol       Date:  2020-04       Impact factor: 7.996

8.  Piloting a Deep Learning Model for Predicting Nuclear BAP1 Immunohistochemical Expression of Uveal Melanoma from Hematoxylin-and-Eosin Sections.

Authors:  Hongrun Zhang; Helen Kalirai; Amelia Acha-Sagredo; Xiaoyun Yang; Yalin Zheng; Sarah E Coupland
Journal:  Transl Vis Sci Technol       Date:  2020-09-01       Impact factor: 3.283

Review 9.  Immunobiology of Uveal Melanoma: State of the Art and Therapeutic Targets.

Authors:  Maria Sofia Basile; Emanuela Mazzon; Paolo Fagone; Antonio Longo; Andrea Russo; Matteo Fallico; Vincenza Bonfiglio; Ferdinando Nicoletti; Teresio Avitabile; Michele Reibaldi
Journal:  Front Oncol       Date:  2019-11-05       Impact factor: 6.244
  9 in total

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