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Literature DB >> 29737848

Synthesis of Unsymmetrical 2,6-Diarylanilines by Palladium-Catalyzed C-H Bond Functionalization Methodology.

Se Hun Kwak¹, Nurbey Gulia^1,2, Olafs Daugulis¹.

Abstract

3,5-Dimethylpyrazole was employed as a monodentate directing group for palladium-catalyzed ortho-sp2 C-H arylation with aryl iodides. The reaction shows good functional group tolerance and outstanding selectivity for mono- ortho-arylation. Ozonolysis of ortho-arylated arylpyrazoles gave acylated biphenylamines that were further arylated to afford unsymmetrically substituted 2,6-diarylacetanilides.

Entities: Chemical Disease Species

Mesh：

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Year: 2018 PMID： 29737848 PMCID： PMC6013069 DOI： 10.1021/acs.joc.8b00659

Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354

28 in total

1. Late-metal catalysts for ethylene homo- and copolymerization.

Authors: S D Ittel; L K Johnson; M Brookhart
Journal: Chem Rev Date: 2000-04-12 Impact factor: 60.622

2. Carboxylate-assisted transition-metal-catalyzed C-H bond functionalizations: mechanism and scope.

Authors: Lutz Ackermann
Journal: Chem Rev Date: 2011-03-09 Impact factor: 60.622

3. RuCl(3)x H(2)O-catalyzed direct arylation of arenes with aryl chlorides in the presence of triphenylphosphine.

Authors: Ning Luo; Zhengkun Yu
Journal: Chemistry Date: 2010-01-18 Impact factor: 5.236

4. Oxidative C-H activation/C-C bond forming reactions: synthetic scope and mechanistic insights.

Authors: Dipannita Kalyani; Nicholas R Deprez; Lopa V Desai; Melanie S Sanford
Journal: J Am Chem Soc Date: 2005-05-25 Impact factor: 15.419

5. Well-defined ruthenium(II) carboxylate as catalyst for direct C-H/C-O bond arylations with phenols in water.

Authors: Lutz Ackermann; Jola Pospech; Harish Kumar Potukuchi
Journal: Org Lett Date: 2012-04-11 Impact factor: 6.005

6. Combined C-H functionalization/C-N bond formation route to carbazoles.

Authors: W C Peter Tsang; Nan Zheng; Stephen L Buchwald
Journal: J Am Chem Soc Date: 2005-10-26 Impact factor: 15.419

7. Mechanistic Studies of Pd(II)-Catalyzed Copolymerization of Ethylene and Vinylalkoxysilanes: Evidence for a β-Silyl Elimination Chain Transfer Mechanism.

Authors: Zhou Chen; Weijun Liu; Olafs Daugulis; Maurice Brookhart
Journal: J Am Chem Soc Date: 2016-12-01 Impact factor: 15.419

Synthesis of Unsymmetrical 2,6-Diarylanilines by Palladium-Catalyzed C-H Bond Functionalization Methodology.

1. Late-metal catalysts for ethylene homo- and copolymerization.

2. Carboxylate-assisted transition-metal-catalyzed C-H bond functionalizations: mechanism and scope.

3. RuCl(3)x H(2)O-catalyzed direct arylation of arenes with aryl chlorides in the presence of triphenylphosphine.

4. Oxidative C-H activation/C-C bond forming reactions: synthetic scope and mechanistic insights.

5. Well-defined ruthenium(II) carboxylate as catalyst for direct C-H/C-O bond arylations with phenols in water.

6. Combined C-H functionalization/C-N bond formation route to carbazoles.

7. Mechanistic Studies of Pd(II)-Catalyzed Copolymerization of Ethylene and Vinylalkoxysilanes: Evidence for a β-Silyl Elimination Chain Transfer Mechanism.

8. Palladium-catalyzed anilide ortho-arylation and subsequent one-pot cyclization to phenanthridines.

9. New nickel(II) diimine complexes and the control of polyethylene microstructure by catalyst design.

10. Carbon-Hydrogen (C-H) Bond Activation at Pd^IV: A Frontier in C-H Functionalization Catalysis.

1. Cobalt-catalyzed, directed arylation of C-H bonds in N-aryl pyrazoles.

2. Regioselective Magnesiation and Zincation Reactions of Aromatics and Heterocycles Triggered by Lewis Acids.