Literature DB >> 29737498

Management of Embolic Stroke of Undetermined Source (ESUS).

Tobias Geisler1, Annerose Mengel2, Ulf Ziemann2, Sven Poli2.   

Abstract

According to the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) classification, embolic stroke of undetermined source (ESUS) has refined the old definition of cryptogenic stroke. More sophisticated criteria and a well-defined diagnostic workup point out the embolic nature of this disease. Because ESUS is associated with a high stroke recurrence, a clear risk prediction and management is of utmost importance to improve prognosis. To date, standard pharmacotherapy consists of antiplatelet drugs and statins. This review attempts to provide an overview on the diagnostic criteria, prognosis, and current clinical trials evaluating the value of direct oral anticoagulants for secondary prevention after ESUS.

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Year:  2018        PMID： 29737498     DOI： 10.1007/s40265-018-0912-8

Source DB:  PubMed          Journal:  Drugs        ISSN： 0012-6667            Impact factor:   9.546


  55 in total

Review 1.  Embolic Stroke of Undetermined Source: A Systematic Review and Clinical Update.

Authors:  Robert G Hart; Luciana Catanese; Kanjana S Perera; George Ntaios; Stuart J Connolly
Journal:  Stroke       Date:  2017-03-06       Impact factor: 7.914

2.  Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.

Authors:  Yongjun Wang; Yilong Wang; Xingquan Zhao; Liping Liu; David Wang; Chunxue Wang; Chen Wang; Hao Li; Xia Meng; Liying Cui; Jianping Jia; Qiang Dong; Anding Xu; Jinsheng Zeng; Yansheng Li; Zhimin Wang; Haiqin Xia; S Claiborne Johnston
Journal:  N Engl J Med       Date:  2013-06-26       Impact factor: 91.245

3.  Embolic stroke of undetermined source: a therapeutic target?

Authors:  Martin Dennis
Journal:  Lancet Neurol       Date:  2014-04       Impact factor: 44.182

4.  Lumpers or splitters: Evaluation and management of embolic stroke of undetermined source.

Authors:  Bryan Eckerle; Ayrton Massaro
Journal:  Neurology       Date:  2016-08-03       Impact factor: 9.910

5.  Predictors for atrial fibrillation detection after cryptogenic stroke: Results from CRYSTAL AF.

Authors:  Vincent N Thijs; Johannes Brachmann; Carlos A Morillo; Rod S Passman; Tommaso Sanna; Richard A Bernstein; Hans-Christoph Diener; Vincenzo Di Lazzaro; Marilyn M Rymer; Laurence Hogge; Tyson B Rogers; Paul D Ziegler; Manish D Assar
Journal:  Neurology       Date:  2015-12-18       Impact factor: 9.910

6.  Relationship between chronic atrial fibrillation and worse outcomes in stroke patients after intravenous thrombolysis.

Authors:  Raymond C S Seet; Yi Zhang; Eelco F Wijdicks; Alejandro A Rabinstein
Journal:  Arch Neurol       Date:  2011-11

7.  Patent Foramen Ovale Closure or Antiplatelet Therapy for Cryptogenic Stroke.

Authors:  Lars Søndergaard; Scott E Kasner; John F Rhodes; Grethe Andersen; Helle K Iversen; Jens E Nielsen-Kudsk; Magnus Settergren; Christina Sjöstrand; Risto O Roine; David Hildick-Smith; J David Spence; Lars Thomassen
Journal:  N Engl J Med       Date:  2017-09-14       Impact factor: 91.245

8.  Patent Foramen Ovale Closure or Anticoagulation vs. Antiplatelets after Stroke.

Authors:  Jean-Louis Mas; Geneviève Derumeaux; Benoît Guillon; Evelyne Massardier; Hassan Hosseini; Laura Mechtouff; Caroline Arquizan; Yannick Béjot; Fabrice Vuillier; Olivier Detante; Céline Guidoux; Sandrine Canaple; Claudia Vaduva; Nelly Dequatre-Ponchelle; Igor Sibon; Pierre Garnier; Anna Ferrier; Serge Timsit; Emmanuelle Robinet-Borgomano; Denis Sablot; Jean-Christophe Lacour; Mathieu Zuber; Pascal Favrole; Jean-François Pinel; Marion Apoil; Peggy Reiner; Catherine Lefebvre; Patrice Guérin; Christophe Piot; Roland Rossi; Jean-Luc Dubois-Randé; Jean-Christophe Eicher; Nicolas Meneveau; Jean-René Lusson; Bernard Bertrand; Jean-Marc Schleich; François Godart; Jean-Benoit Thambo; Laurent Leborgne; Patrik Michel; Luc Pierard; Guillaume Turc; Martine Barthelet; Anaïs Charles-Nelson; Christian Weimar; Thierry Moulin; Jean-Michel Juliard; Gilles Chatellier
Journal:  N Engl J Med       Date:  2017-09-14       Impact factor: 91.245

9.  Cryptogenic stroke and underlying atrial fibrillation.

Authors:  Tommaso Sanna; Hans-Christoph Diener; Rod S Passman; Vincenzo Di Lazzaro; Richard A Bernstein; Carlos A Morillo; Marilyn Mollman Rymer; Vincent Thijs; Tyson Rogers; Frank Beckers; Kate Lindborg; Johannes Brachmann
Journal:  N Engl J Med       Date:  2014-06-26       Impact factor: 91.245

10.  Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial.

Authors:  Hans-Christoph Diener; Julien Bogousslavsky; Lawrence M Brass; Claudio Cimminiello; Laszlo Csiba; Markku Kaste; Didier Leys; Jordi Matias-Guiu; Hans-Jürgen Rupprecht
Journal:  Lancet       Date:  2004 Jul 24-30       Impact factor: 79.321
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  3 in total

1.  Prevalence of Left Atrial Septal Pouch Among Patients with Embolic Stroke of Undetermined Source Or Stroke of Known Etiology: a Retrospective Study.

Authors:  Hugo Steyaert; Jose Castro Rodriguez; Marie-Dominique Gazagnes; Marielle Morissens
Journal:  J Transl Int Med       Date:  2022-04-09

2.  Prolonged ECG with a novel recorder utilizing electrode belt and mobile device in patients with recent embolic stroke of undetermined source: A pilot study.

Authors:  Tuomas Jussi Lumikari; Jani Pirinen; Jukka Putaala; Gerli Sibolt; Anne Kerola; Sami Pakarinen; Mika Lehto; Tuomo Nieminen
Journal:  Ann Noninvasive Electrocardiol       Date:  2020-09-27       Impact factor: 1.468

3.  Left Ventricular Diastolic Dysfunction as Predictor of Unfavorable Prognosis After ESUS.

Authors:  Agata Bielecka-Dabrowa; Paulina Gasiorek; Andrzej Wittczak; Agata Sakowicz; Ibadete Bytyçi; Maciej Banach
Journal:  J Multidiscip Healthc       Date:  2021-03-09
  3 in total

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