Yi You1, Wenchief Chen2, Baiyu Zhong3, Ziqiang Song3, Xichuan Yang3. 1. Department of Dermatology, Southwest Hospital, Third Military Medical University, Chongqing, China. youyi_cq@163.com. 2. Department of Dermatology and Allergy, Technische Universitaet Muenchen, Munich, Germany. 3. Department of Dermatology, Southwest Hospital, Third Military Medical University, Chongqing, China.
Abstract
BACKGROUND: Disseminated nocardiosis is a rare disease mostly occurring in immunocompromised patients. METHODS: We report a case of disseminated nocardiosis in a diabetic patient with both pulmonary and cutaneous involvement. Nocardia elegans was isolated and identified using the 16s ribosomal RNA gene sequence data. RESULTS: Clinical improvement was observed within 3 months after initiation of antimicrobial treatment with oral doxycycline, trimethoprim-sulfamethoxazole and intravenous penicillin, but the patient died 5 months later after arbitrary discontinuation of the treatment. CONCLUSIONS: This is the first case report of disseminated nocardiosis caused by Nocardia elegans in China.
BACKGROUND: Disseminated nocardiosis is a rare disease mostly occurring in immunocompromised patients. METHODS: We report a case of disseminated nocardiosis in a diabeticpatient with both pulmonary and cutaneous involvement. Nocardia elegans was isolated and identified using the 16s ribosomal RNA gene sequence data. RESULTS: Clinical improvement was observed within 3 months after initiation of antimicrobial treatment with oral doxycycline, trimethoprim-sulfamethoxazole and intravenous penicillin, but the patient died 5 months later after arbitrary discontinuation of the treatment. CONCLUSIONS: This is the first case report of disseminated nocardiosis caused by Nocardia elegans in China.
Authors: W L Liu; C C Lai; W C Ko; Y H Chen; H J Tang; Y L Huang; Y T Huang; P R Hsueh Journal: Eur J Clin Microbiol Infect Dis Date: 2011-04-03 Impact factor: 3.267
Authors: S P Buckwalter; S L Olson; B J Connelly; B C Lucas; A A Rodning; R C Walchak; S M Deml; S L Wohlfiel; N L Wengenack Journal: J Clin Microbiol Date: 2015-12-04 Impact factor: 5.948