Literature DB >> 29735705

Taming unruly chloride channel inhibitors with rational design.

Rebecka J Sepela1, Jon T Sack2.   

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Year:  2018        PMID： 29735705      PMCID： PMC6003517          DOI： 10.1073/pnas.1805589115

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  10 in total

1.  Kv2 channel regulation of action potential repolarization and firing patterns in superior cervical ganglion neurons and hippocampal CA1 pyramidal neurons.

Authors:  Pin W Liu; Bruce P Bean
Journal:  J Neurosci       Date:  2014-04-02       Impact factor: 6.167

2.  A selective class of inhibitors for the CLC-Ka chloride ion channel.

Authors:  Anna K Koster; Chase A P Wood; Rhiannon Thomas-Tran; Tanmay S Chavan; Jonas Almqvist; Kee-Hyun Choi; J Du Bois; Merritt Maduke
Journal:  Proc Natl Acad Sci U S A       Date:  2018-04-18       Impact factor: 11.205

3.  Disruption of ClC-3, a chloride channel expressed on synaptic vesicles, leads to a loss of the hippocampus.

Authors:  S M Stobrawa; T Breiderhoff; S Takamori; D Engel; M Schweizer; A A Zdebik; M R Bösl; K Ruether; H Jahn; A Draguhn; R Jahn; T J Jentsch
Journal:  Neuron       Date:  2001-01       Impact factor: 17.173

4.  Fluorescent saxitoxins for live cell imaging of single voltage-gated sodium ion channels beyond the optical diffraction limit.

Authors:  Alison E Ondrus; Hsiao-lu D Lee; Shigeki Iwanaga; William H Parsons; Brian M Andresen; W E Moerner; J Du Bois
Journal:  Chem Biol       Date:  2012-07-27

5.  Molecular switch for CLC-K Cl- channel block/activation: optimal pharmacophoric requirements towards high-affinity ligands.

Authors:  Antonella Liantonio; Alessandra Picollo; Giuseppe Carbonara; Giuseppe Fracchiolla; Paolo Tortorella; Fulvio Loiodice; Antonio Laghezza; Elena Babini; Giovanni Zifarelli; Michael Pusch; Diana Conte Camerino
Journal:  Proc Natl Acad Sci U S A       Date:  2008-01-23       Impact factor: 11.205

Review 6.  Cell biology and physiology of CLC chloride channels and transporters.

Authors:  Tobias Stauber; Stefanie Weinert; Thomas J Jentsch
Journal:  Compr Physiol       Date:  2012-07       Impact factor: 9.090

7.  Discovery of potent CLC chloride channel inhibitors.

Authors:  Kimberly Matulef; Andrew E Howery; Li Tan; William R Kobertz; J Du Bois; Merritt Maduke
Journal:  ACS Chem Biol       Date:  2008-07-18       Impact factor: 5.100

8.  Molecular determinants of differential pore blocking of kidney CLC-K chloride channels.

Authors:  Alessandra Picollo; Antonella Liantonio; Maria Paola Didonna; Laura Elia; Diana Conte Camerino; Michael Pusch
Journal:  EMBO Rep       Date:  2004-05-28       Impact factor: 8.807

9.  In-vivo administration of CLC-K kidney chloride channels inhibitors increases water diuresis in rats: a new drug target for hypertension?

Authors:  Antonella Liantonio; Gianluca Gramegna; Giulia M Camerino; Maria M Dinardo; Antonia Scaramuzzi; Maria A Potenza; Monica Montagnani; Giuseppe Procino; Domenica R Lasorsa; Lisa Mastrofrancesco; Antonio Laghezza; Giuseppe Fracchiolla; Fulvio Loiodice; Maria G Perrone; Angela Lopedota; Salvatore Conte; Rosa Penza; Giovanna Valenti; Maria Svelto; Diana Conte Camerino
Journal:  J Hypertens       Date:  2012-01       Impact factor: 4.844

10.  A 18F-labeled saxitoxin derivative for in vivo PET-MR imaging of voltage-gated sodium channel expression following nerve injury.

Authors:  Aileen Hoehne; Deepak Behera; William H Parsons; Michelle L James; Bin Shen; Preeti Borgohain; Deepika Bodapati; Archana Prabhakar; Sanjiv S Gambhir; David C Yeomans; Sandip Biswal; Frederick T Chin; J Du Bois
Journal:  J Am Chem Soc       Date:  2013-11-21       Impact factor: 15.419
  10 in total
  1 in total

1.  Reduced Expression of TMEM16A Impairs Nitric Oxide-Dependent Cl- Transport in Retinal Amacrine Cells.

Authors:  Tyler Christopher Rodriguez; Li Zhong; Hailey Simpson; Evanna Gleason
Journal:  Front Cell Neurosci       Date:  2022-07-27       Impact factor: 6.147
  1 in total

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