B J van der Knoop1, K J Oostrom2, I A Zonnenberg3, M M van Weissenbruch4, R J Vermeulen5, J I P de Vries6. 1. Department of Obstetrics and Gynaecology, VU University Medical Center, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands; Neuroscience Campus, VU University, Amsterdam, The Netherlands. Electronic address: b.vanderknoop@vumc.nl. 2. Dept of Pediatric Psychology, VU University Medical Center, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands. Electronic address: KJ.oostrom@vumc.nl. 3. Department of Neonatology, VU University Medical Center, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands. Electronic address: i.zonnenberg@vumc.nl. 4. Department of Neonatology, VU University Medical Center, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands. Electronic address: m.vanweissenbruch@vumc.nl. 5. Department of Child Neurology, VU University Medical Center, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands. Electronic address: jeroen.vermeulen@mumc.nl. 6. Department of Obstetrics and Gynaecology, VU University Medical Center, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands; Research Institute MOVE, Amsterdam, The Netherlands. Electronic address: jip.devries@vumc.nl.
Abstract
BACKGROUND: Maternal trauma complicates pregnancy in approximately 7%. Long-term development of children exposed to maternal trauma is unknown. AIM: To determine neurobehavioural outcome of children (6-18 years) born after maternal trauma in pregnancy compared to a matched control group. STUDY DESIGN: Case-control study performed at a tertiary medical centre. SUBJECTS: All consecutive children born after maternal hospitalization for trauma during pregnancy between 1995 and 2005. Controls were children born at the same hospital and period after an uneventful pregnancy. OUTCOME MEASURES: Trauma type and severity (Injury Severity Score, ≥9: severe); information from medical files at admission (cases). All mothers filled out two questionnaires about the infant; 1. concerning health, motor development and educational level, 2. concerning behavioural development through the validated Dutch version of the Child Behavior Checklist (CBCL). RESULTS: Questionnaires were returned by 34 cases and 28 controls. The traumas concerned mainly motor vehicle accidents and falls, and 3/34 had severe injuries. No differences in health, motor development, educational level and CBCL was found between the cases and controls, except for more hospitalization in the cases (p = 0.009). CONCLUSION: Long-term follow-up of a limited population of children 6-18 years after exposure of mainly non-severe trauma before birth is similar to a control population except for unexplained more hospitalization in the cases.
BACKGROUND:Maternal trauma complicates pregnancy in approximately 7%. Long-term development of children exposed to maternal trauma is unknown. AIM: To determine neurobehavioural outcome of children (6-18 years) born after maternal trauma in pregnancy compared to a matched control group. STUDY DESIGN: Case-control study performed at a tertiary medical centre. SUBJECTS: All consecutive children born after maternal hospitalization for trauma during pregnancy between 1995 and 2005. Controls were children born at the same hospital and period after an uneventful pregnancy. OUTCOME MEASURES: Trauma type and severity (Injury Severity Score, ≥9: severe); information from medical files at admission (cases). All mothers filled out two questionnaires about the infant; 1. concerning health, motor development and educational level, 2. concerning behavioural development through the validated Dutch version of the Child Behavior Checklist (CBCL). RESULTS: Questionnaires were returned by 34 cases and 28 controls. The traumas concerned mainly motor vehicle accidents and falls, and 3/34 had severe injuries. No differences in health, motor development, educational level and CBCL was found between the cases and controls, except for more hospitalization in the cases (p = 0.009). CONCLUSION: Long-term follow-up of a limited population of children 6-18 years after exposure of mainly non-severe trauma before birth is similar to a control population except for unexplained more hospitalization in the cases.
Authors: B J van der Knoop; I A Zonnenberg; J I M L Verbeke; L S de Vries; L R Pistorius; M M van Weissenbruch; R J Vermeulen; J I P de Vries Journal: Ultrasound Obstet Gynecol Date: 2020-09 Impact factor: 7.299