| Literature DB >> 29735020 |
Martha A Belury1, Rachel M Cole2, Deena B Snoke2, Taylor Banh2, Austin Angelotti2.
Abstract
Dietary fat quality, especially the intake of specific types of fatty acids, impacts the risk of many chronic diseases, including cardiovascular diseases, certain cancers and type 2 diabetes (T2DM). A recent pooled analysis involving 20 studies from around the world revealed that higher linoleic acid (18:2n-6 LA) biomarker is associated with dose-dependent decreases in the incidence of T2DM. This latest study corroborates earlier cross-sectional studies and intervention trials showing that biomarkers of LA intake are associated with reduced risk of T2DM and better glycemic control and/or insulin sensitivity. This review highlights key clinical trials that have evaluated the role of LA in glycemia and the related condition, insulin sensitivity.Entities:
Keywords: Adiponectin; Insulin resistance; Linoleic acid; Monounsaturated fat; Polyunsaturated fat; Saturated fat
Mesh:
Substances:
Year: 2018 PMID: 29735020 DOI: 10.1016/j.plefa.2018.03.001
Source DB: PubMed Journal: Prostaglandins Leukot Essent Fatty Acids ISSN: 0952-3278 Impact factor: 4.006