Literature DB >> 2973478

Scrotal dermatitis caused by 5-fluorouracil (Efudex).

W B Shelley1, E D Shelley.   

Abstract

Four patients are described who experienced an acute episode of eczematous dermatitis of the scrotum where 5-fluorouracil (Efudex) cream had inadvertently been applied in the course of treating warts and keratoses. The reaction was not allergic in origin but resulted from the unique absorptive capabilities of scrotal skin, which permitted entrance and local toxic effects of 5-fluorouracil.

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Year:  1988        PMID： 2973478     DOI： 10.1016/s0190-9622(88)70252-2

Source DB:  PubMed          Journal:  J Am Acad Dermatol        ISSN： 0190-9622            Impact factor:   11.527


  3 in total

Review 1.  Scrotal Dermatitis - Can we Consider it as a Separate Entity?

Authors:  Ajay Krishnan; Sumit Kar
Journal:  Oman Med J       Date:  2013-09

2.  Exuberant inflammatory reaction to occlusion of topical 5-fluorouracil (FU) under a continuous positive airway pressure (CPAP) mask: A warning to dermatologists and patients.

Authors:  Jameson Loyal; Michael Romano; Joseph C Pierson
Journal:  JAAD Case Rep       Date:  2016-07-14

3.  Topical Application of 5-Fluorouracil Associated with Distant Seborrheic Dermatitis-like Eruption: Case Report and Review of Seborrheic Dermatitis Cutaneous Reactions after Systemic or Topical Treatment with 5-Fluorouracil.

Authors:  Tyler Werbel; Philip R Cohen
Journal:  Dermatol Ther (Heidelb)       Date:  2018-07-26
  3 in total

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