| Literature DB >> 29734045 |
Randy R Brutkiewicz1, Laura Yunes-Medina2, Jianyun Liu2.
Abstract
Many reviews on the CD1d/NKT cell axis focus on the ability of CD1d-restricted NKT cells to serve as effector cells in a variety of disorders, be they infectious diseases, cancer or autoimmunity. In contrast, here, we discuss the ways that viruses, bacteria and tumor cells can evade the CD1d/NKT cell axis. As a result, these disease states have a better chance to establish a foothold and potentially cause problems for the subsequent adaptive immune response, as the host tries to rid itself of infections or tumors.Entities:
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Year: 2018 PMID: 29734045 PMCID: PMC6004260 DOI: 10.1016/j.coi.2018.04.021
Source DB: PubMed Journal: Curr Opin Immunol ISSN: 0952-7915 Impact factor: 7.486