| Literature DB >> 29733758 |
Helena Medina Cruz1, Juliana Custódio Miguel Cruz1, Elisangela Ferreira Da Silva1, Moyra Machado Portilho1, Vanessa Alves Marques1, Lia Laura Lewis-Ximenez1, Elisabeth Lampe1, Livia Melo Villar1.
Abstract
Dried blood spots (DBSs) could be an alternative to serum for hepatitis B virus (HBV) and hepatitis C virus (HCV) diagnosis. This study aims to evaluate two enzyme immunoassays (EIAs) for HBsAg and anti-HCV detection using DBS. Serum was tested using commercial EIA. DBS was tested using optimized EIA developed for serum and commercial EIA developed for DBS (Imunoscreen). Concordances between DBS and serum samples for both markers and EIAs were higher than 97%. Both EIAs demonstrated good performance for HBsAg and anti-HCV detection using DBS, and these methods could be used unchangeably increasing the access for HBV and HCV diagnosis.Entities:
Keywords: dried blood spots; enzyme immunoassays; hepatitis B; hepatitis C
Mesh：
Year: 2018 PMID： 29733758 DOI： 10.1080/15321819.2018.1470095
Source DB: PubMed Journal: J Immunoassay Immunochem ISSN： 1532-1819