Monique Dodd1, Allen Adolphe2, Alisha Parada2, Meghan Brett2, Karissa Culbreath1, Renée-Claude Mercier3. 1. University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America; TriCore Reference Laboratories, Albuquerque, New Mexico, United States of America. 2. University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America. 3. University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America. Electronic address: RMercier@salud.unm.edu.
Abstract
INTRODUCTION: Adult pharyngitis is rarely attributable to group A streptococci. Utilization of a rapid streptococcal antigen test (RADT) may improve appropriate prescribing for bacterial pharyngitis. METHODS: Clinic 1 performed RADTs with subsequent Group A DNA probe test (GADNA) from November 2014-March 2015 and November 2015-March 2016 while Clinic 2 was the control clinic, then implemented the RADT with a GADNA from November 2015-March 2016. All GADNA results were obtained for each clinic from October 2013-March 2016. RESULTS: At Clinic 1, 22.2% versus 8.5% of patients received inappropriately prescribed antibiotics for a GADNA or RADT result, respectively (p=0.048). For Clinic 2, 51.1% compared to 21.4% of patients were inappropriately prescribed antibiotic for a GADNA or RADT result, respectively (p=0.038). Overall, the total GADNA without RADT testing or RADTs with subsequent GADNA testing, 41.6% versus 11% of patients were inappropriately prescribed antibiotics, respectively (p=<0.0001). CONCLUSION: Utilizing the RADT prevented unnecessary prescribing of antibiotics in adults.
INTRODUCTION: Adult pharyngitis is rarely attributable to group A streptococci. Utilization of a rapid streptococcal antigen test (RADT) may improve appropriate prescribing for bacterial pharyngitis. METHODS: Clinic 1 performed RADTs with subsequent Group A DNA probe test (GADNA) from November 2014-March 2015 and November 2015-March 2016 while Clinic 2 was the control clinic, then implemented the RADT with a GADNA from November 2015-March 2016. All GADNA results were obtained for each clinic from October 2013-March 2016. RESULTS: At Clinic 1, 22.2% versus 8.5% of patients received inappropriately prescribed antibiotics for a GADNA or RADT result, respectively (p=0.048). For Clinic 2, 51.1% compared to 21.4% of patients were inappropriately prescribed antibiotic for a GADNA or RADT result, respectively (p=0.038). Overall, the total GADNA without RADT testing or RADTs with subsequent GADNA testing, 41.6% versus 11% of patients were inappropriately prescribed antibiotics, respectively (p=<0.0001). CONCLUSION: Utilizing the RADT prevented unnecessary prescribing of antibiotics in adults.
Authors: Shana A B Burrowes; Alec Rader; Pengsheng Ni; Mari-Lynn Drainoni; Tamar F Barlam Journal: Open Forum Infect Dis Date: 2020-03-03 Impact factor: 3.835
Authors: Joshua L Eudy; Andrea M Pallotta; Elizabeth A Neuner; Gretchen L Brummel; Michael J Postelnick; Lucas T Schulz; Emily S Spivak; Rebekah H Wrenn Journal: Open Forum Infect Dis Date: 2020-10-24 Impact factor: 3.835