I N Belugina1, N Z Yagovdik1, O S Belugina2, S N Belugin3. 1. Department of Venereology and Dermatology, Belarusian State Medical University, Minsk, Belarus. 2. Department of Psychiatry, Belarusian State Medical University, Minsk, Belarus. 3. Department of Radiation and Environmental Medicine, Belarusian State Medical University, Minsk, Belarus.
Abstract
BACKGROUND: The early occurrence of atopic dermatitis in infants may be influenced by urban air pollution. OBJECTIVE: The aim of this study was to determine the relationship between incidences of infantile eczema in children under 2 years of age and urban outdoor environmental factors. METHODS: A 11-year population-based study was conducted in retrospective design. The age/gender-adjusted incidence rates of infantile eczema were determined using the data of outpatient visits. We analysed 1965 cases with atopic dermatitis including infantile eczema in relation to the annual means of outdoor monitoring data from 2005 through 2015 in Minsk. Logistic regression and principal component analysis were performed to determine association between the annual means of air pollutants, meteorological variables and incidences of infantile eczema. RESULTS: Higher mean annual carbon monoxide, ammonia, formaldehyde, lead, particulate matter and ground-level ozone were associated with high incidence rates of infantile eczema both in boys and girls. Higher nitrogen dioxide was associated with high incidence rates of infantile eczema in girls 1-2 years of age and boys 0-2 years of age. There were identified by principal component analysis five combinations of pollutants and meteorological factors. High incidence rates of infantile eczema were associated with the combinations contained higher levels of air pollutants and ultraviolet index, or lower β-activity of the radionuclide-associated aerosols. The higher phenol and formaldehyde levels the higher incidence rates of infantile eczema were observed among boys 0-1 years of age and girls 1-2 years of age. The higher total column ozone with lower lead level was associated with low incidence rates of infantile eczema among boys and girls 1-2 years of age. CONCLUSION: Urban outdoor air pollutants and their combination with meteorological conditions may impact onset of infantile eczema in both genders.
BACKGROUND: The early occurrence of atopic dermatitis in infants may be influenced by urban air pollution. OBJECTIVE: The aim of this study was to determine the relationship between incidences of infantile eczema in children under 2 years of age and urban outdoor environmental factors. METHODS: A 11-year population-based study was conducted in retrospective design. The age/gender-adjusted incidence rates of infantile eczema were determined using the data of outpatient visits. We analysed 1965 cases with atopic dermatitis including infantile eczema in relation to the annual means of outdoor monitoring data from 2005 through 2015 in Minsk. Logistic regression and principal component analysis were performed to determine association between the annual means of air pollutants, meteorological variables and incidences of infantile eczema. RESULTS: Higher mean annual carbon monoxide, ammonia, formaldehyde, lead, particulate matter and ground-level ozone were associated with high incidence rates of infantile eczema both in boys and girls. Higher nitrogen dioxide was associated with high incidence rates of infantile eczema in girls 1-2 years of age and boys 0-2 years of age. There were identified by principal component analysis five combinations of pollutants and meteorological factors. High incidence rates of infantile eczema were associated with the combinations contained higher levels of air pollutants and ultraviolet index, or lower β-activity of the radionuclide-associated aerosols. The higher phenol and formaldehyde levels the higher incidence rates of infantile eczema were observed among boys 0-1 years of age and girls 1-2 years of age. The higher total column ozone with lower lead level was associated with low incidence rates of infantile eczema among boys and girls 1-2 years of age. CONCLUSION: Urban outdoor air pollutants and their combination with meteorological conditions may impact onset of infantile eczema in both genders.
Authors: Irini M Dijkhoff; Barbara Drasler; Bedia Begum Karakocak; Alke Petri-Fink; Giuseppe Valacchi; Marc Eeman; Barbara Rothen-Rutishauser Journal: Part Fibre Toxicol Date: 2020-07-25 Impact factor: 9.400
Authors: Bjorn R Thomas; Xiang L Tan; Shagayegh Javadzadeh; Elizabeth J Robinson; Bryan S McDonald; Malvina A Krupiczojc; Syedia R Rahman; Samiha Rahman; Rehana A Ahmed; Rubina Begum; Habiba Khanam; David P Kelsell; Jonathan Grigg; Robert J Knell; Edel A O'Toole Journal: JID Innov Date: 2021-10-09
Authors: Mengting Liao; Yi Xiao; Shenxin Li; Juan Su; Ji Li; Bin Zou; Xiang Chen; Minxue Shen Journal: Int J Environ Res Public Health Date: 2022-08-13 Impact factor: 4.614