Literature DB >> 29730093

Adverse events and satisfaction with use of intranasal midazolam for emergency department procedures in children.

Laurie Malia1, V Matt Laurich2, Jesse J Sturm3.   

Abstract

PURPOSE: Procedural sedation is commonly performed in the emergency department (ED). Having safe and fast means of providing sedation and anxiolysis to children is important for the child's tolerance of the procedure, parent satisfaction and efficient patient flow in the ED.
OBJECTIVE: To evaluate fasting times associated with the administration of intranasal midazolam (INM) and associated complications. Secondary objectives included assessing provider and caregiver satisfaction scores.
METHODS: A prospective observational study was conducted in children presenting to an urban pediatric emergency department who received INM for anxiolysis for a procedure or imaging. Data collected included last solid and liquid intake, procedure performed, sedation depth, adverse events and parent and provider satisfaction.
RESULTS: 112 patients were enrolled. The mean age was 3.8 years. There were no adverse events experienced by any patients. Laceration repair was the most common reason for INM use. The median depth of sedation was 2.0 (cooperative/tranquil). The median liquid NPO time was 172.5 min and the median NPO time for solids was 194.0 min. 29.8% were NPO for liquids ≤2 h and 62.5% were NPO for solids ≤2 h. Parent and provider satisfaction was high: 90.4% of parents' and 88.4% of providers' satisfaction scores were a 4 or 5 on a 5 point Likert scale.
CONCLUSION: Our data suggest that short NPO of both solids and liquids are safe for the use of INM. Additionally, parent and provider satisfaction scores were high with the use of INM. Published by Elsevier Inc.

Entities:  

Keywords:  Anxiolysis; Intranasal midazolam; Satisfaction

Mesh:

Substances:

Year:  2018        PMID: 29730093     DOI: 10.1016/j.ajem.2018.04.063

Source DB:  PubMed          Journal:  Am J Emerg Med        ISSN: 0735-6757            Impact factor:   2.469


  2 in total

1.  Comparison of preadministered and coadministered lidocaine for treating pain and distress associated with intranasal midazolam administration in children: A randomized clinical trial.

Authors:  Nicole C O'Connell; Hilary A Woodward; Pamela L Flores-Sanchez; Son H McLaren; Maria Ieni; Kenneth W McKinley; Sripriya T Shen; Peter S Dayan; Daniel S Tsze
Journal:  J Am Coll Emerg Physicians Open       Date:  2020-08-26

2.  Sleep deprivation did not enhance the success rate of chloral hydrate sedation for non-invasive procedural sedation in pediatric patients.

Authors:  Yu Cui; Langtao Guo; Qixia Mu; Qin Cheng; Lu Kang; Yani He; Min Tang; Qunying Wu
Journal:  PLoS One       Date:  2021-01-12       Impact factor: 3.240

  2 in total

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