Jin Hee Moon1, Sung Hye Koh2, Sun-Young Park2, Ji-Young Hwang1, Ji Young Woo1. 1. 1 Department of Radiology, Hallym University Kangnam Sacred Heart Hospital, Seoul, Republic of Korea. 2. 2 Department of Radiology, Hallym University Medical Center, Hallym Sacred Heart Hospital, Gyeonggi-do, Republic of Korea.
Abstract
BACKGROUND: The maximum value of the strain ratio (SR) is a newly developed measure in strain-elastography. PURPOSE: To prospectively compare the diagnostic performance of three different measures of strain-elastography, the maximum value of the SR (SRmax), the average value of the SR (SRave), and the color map, for differentiating benign and malignant breast lesions. MATERIAL AND METHODS: We obtained the SRmax and SRave of 314 lesions from 290 patients with the tissue to nodule SR and color map using a five-degree scoring system. The diagnostic performances of the SRmax, SRave, and color map were compared after obtaining the area under the receiver operating characteristic (ROC) curves (AUCs) of each parameter. RESULTS: The AUC of the SRmax (0.7674) was larger than the AUCs of the SRave (0.7138) and color map (0.6324), with statistical significance ( P = 0.0383 for SRmax vs. SRave, P = 0.0000 for SRmax vs. color map). The AUC of the SRave was larger than that of the color map; however, there was no significant difference. The optimal cut-off point of the SRmax that balanced the sensitivity (91.12%) and specificity (50.81%) was 5.16. CONCLUSION: The SRmax is a more reliable diagnostic tool than the SRave and color map for differentiating benign and malignant breast lesions.
BACKGROUND: The maximum value of the strain ratio (SR) is a newly developed measure in strain-elastography. PURPOSE: To prospectively compare the diagnostic performance of three different measures of strain-elastography, the maximum value of the SR (SRmax), the average value of the SR (SRave), and the color map, for differentiating benign and malignant breast lesions. MATERIAL AND METHODS: We obtained the SRmax and SRave of 314 lesions from 290 patients with the tissue to nodule SR and color map using a five-degree scoring system. The diagnostic performances of the SRmax, SRave, and color map were compared after obtaining the area under the receiver operating characteristic (ROC) curves (AUCs) of each parameter. RESULTS: The AUC of the SRmax (0.7674) was larger than the AUCs of the SRave (0.7138) and color map (0.6324), with statistical significance ( P = 0.0383 for SRmax vs. SRave, P = 0.0000 for SRmax vs. color map). The AUC of the SRave was larger than that of the color map; however, there was no significant difference. The optimal cut-off point of the SRmax that balanced the sensitivity (91.12%) and specificity (50.81%) was 5.16. CONCLUSION: The SRmax is a more reliable diagnostic tool than the SRave and color map for differentiating benign and malignant breast lesions.