Impact of Ethnicity, Sex, and Socio-Economic Status on the Risk for Heart Failure Readmission: The Importance of Context.

Background: Hispanics are a fast-growing minority in the United States and have a high risk for the development of heart failure (HF). Hispanics have higher HF-related hospital readmission rates compared with non-Hispanics. However, the risk of readmission in a largely disadvantaged and majority Hispanic population has not been evaluated.
Methods: We analyzed data for patients discharged with a principal discharge diagnosis of HF from the University of New Mexico Hospital from 2010-2014. Student t-test and chi-square analysis were used to assess the unadjusted associations between baseline characteristics and 30-day readmission rate. Multivariable logistic regression modeling evaluated the associations between 30-day hospital readmission rate, socio-demographic characteristics, and clinical variables.
Results: A total of 1,594 patients were included in our analysis. Mean age (SD) was 63.1 ± 14 and 62.9 ±13.8 (P=.07) for Hispanics and non-Hispanics, respectively. Sixty percent of Hispanics had HF with reduced ejection fraction compared with 53.9% of non-Hispanics (P=.012). In unadjusted analysis, Hispanic ethnicity was associated with a two-fold increase in HF readmission rate compared with non-Hispanic ethnicity (OR 2.0, 95% CI 1.5-2.7). In fully adjusted models, Hispanic ethnicity showed an 80% increase in HF readmission rate compared with non-Hispanic ethnicity (OR 1.8, 95% CI 1.2-2.6).
Conclusion: Among patients from a socioeconomically disadvantaged background living in a Hispanic-majority area, being Hispanic is associated with higher odds of 30-day hospital re-admission after adjusting for demographic, clinical and socioeconomic covariates. Our findings show that further research is needed to understand disparities in Hispanic's heart failure-related outcomes.