Literature DB >> 29723860

Animal Models of Proliferative Vitreoretinopathy and Their Use in Pharmaceutical Investigations.

Huiyuan Hou1,2, Eric Nudleman3, Robert N Weinreb3.   

Abstract

Animal models are indispensable for pharmaceutical investigations. However, investigators often have difficulty choosing the appropriate modal for their research. To provide a comprehensive and convenient source of information about animal models of proliferative vitreoretinopathy (PVR), the current review sorted and analyzed representative animal models for pharmacotherapy of PVR since 1976.
© 2018 S. Karger AG, Basel.

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Keywords:  Animal model; Drug; Pharmacotherapy; Proliferative vitreoretinopathy

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Year:  2018        PMID： 29723860     DOI： 10.1159/000488492

Source DB:  PubMed          Journal:  Ophthalmic Res        ISSN： 0030-3747            Impact factor:   3.031


  6 in total

1.  Phosphoinositide 3-kinase δ inactivation prevents vitreous-induced activation of AKT/MDM2/p53 and migration of retinal pigment epithelial cells.

Authors:  Haote Han; Na Chen; Xionggao Huang; Bing Liu; Jingkui Tian; Hetian Lei
Journal:  J Biol Chem       Date:  2019-08-29       Impact factor: 5.157

2.  Cross-talk between microRNA-let7c and transforming growth factor-β2 during epithelial-to-mesenchymal transition of retinal pigment epithelial cells.

Authors:  Qu-Zhen Deji; Feng Yan; Wang-Dui Zhaba; Ya-Jun Liu; Jie Yin; Zhen-Ping Huang
Journal:  Int J Ophthalmol       Date:  2020-05-18       Impact factor: 1.779

3.  Topical delivery of a small molecule RUNX1 transcription factor inhibitor for the treatment of proliferative vitreoretinopathy.

Authors:  Santiago Delgado-Tirado; Dhanesh Amarnani; Guannan Zhao; Elizabeth J Rossin; Dean Eliott; John B Miller; Whitney A Greene; Leslie Ramos; Said Arevalo-Alquichire; David Leyton-Cifuentes; Lucia Gonzalez-Buendia; Daniela Isaacs-Bernal; Hannah A B Whitmore; Natalia Chmielewska; Brandon V Duffy; Eric Kim; Heuy-Ching Wang; Jose M Ruiz-Moreno; Leo A Kim; Joseph F Arboleda-Velasquez
Journal:  Sci Rep       Date:  2020-11-30       Impact factor: 4.379

4.  The role of vitreous cortex remnants in proliferative vitreoretinopathy formation demonstrated by histopathology: A case report.

Authors:  Koen A van Overdam; Eelco M Busch; Robert M Verdijk; Claire W A Pennekamp
Journal:  Am J Ophthalmol Case Rep       Date:  2021-10-07

5.  Yes-associated protein is essential for proliferative vitreoretinopathy development via the epithelial-mesenchymal transition in retinal pigment epithelial fibrosis.

Authors:  Wei Zhang; Jing Li
Journal:  J Cell Mol Med       Date:  2021-10-01       Impact factor: 5.310

6.  Endogenous or Exogenous Retinal Pigment Epithelial Cells: A Comparison of Two Experimental Animal Models of Proliferative Vitreoretinopathy.

Authors:  Chee Wai Wong; Joanna Marie Fianza Busoy; Ning Cheung; Veluchamy Amutha Barathi; Gert Storm; Tina T Wong
Journal:  Transl Vis Sci Technol       Date:  2020-08-31       Impact factor: 3.283
  6 in total

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