Literature DB >> 29722289

Corrigendum: Transcription factor VdCmr1 is required for pigment production, protection from UV irradiation, and regulates expression of melanin biosynthetic genes in Verticillium dahliae.

Yonglin Wang1, Xiaoping Hu2, Yulin Fang1, Amy Anchieta3, Polly H Goldman3, Gustavo Hernandez3, Steven J Klosterman3.   

Abstract

Entities:  

Keywords:  DHN; fungi; melanin; pathogenicity; pigment; regulation

Year:  2018        PMID: 29722289      PMCID: PMC7008214          DOI: 10.1099/mic.0.000661

Source DB:  PubMed          Journal:  Microbiology        ISSN: 1350-0872            Impact factor:   2.777


× No keyword cloud information.
There was an error in Fig. 6 of the published article. In the HOG-MAPK cascade the text ‘Ste11’ should be replaced by ‘Ssk2’. The corrected Fig. 6 is shown on the next page.
Fig. 6.

Schematic diagram depicting VdCmr1-dependent DHN melanogenesis in V. dahliae. Key proteins involving the DHN melanogenesis pathway are depicted from the initial acetyl-CoA or malonyl-CoA precursors through production of DHN melanin [4]. The Ssk2-Pbs2-Hog1 signalling cascade is a regulator of melanin biosynthesis in V. dahliae [14]. The transcription factor VdMcm1 and the polyketide chain shortening enzyme Vayg1 also modulate DHN melanogenesis. Our work identified several key genes that contribute to DHN melanin biosynthesis and that are regulated by VdCmr1. Some of these genes are found within the cluster enriched in DHN melanin biosynthetic genes within the V. dahliae genome. The non-melanin synthesis-related genes, up or downregulated during microsclerotial development [7], are regulated by VdCmr1 as demonstrated in this study; these genes VDAG_03079 (catalase) and VDAG_08741 VDECH (endochitinase, VDAG_08741) also reside outside of the gene cluster enriched in melanin biosynthetic genes. aVDAG_03665 may catalyse both T4HN and T3HN reductase steps based upon the strong homology of VDAG_03665 to the THR1 protein of Colletotrichum lagenarium, which can catalyse both T4HN and T3HN reductase steps [41].

The author apologizes for any inconvenience caused. Schematic diagram depicting VdCmr1-dependent DHN melanogenesis in V. dahliae. Key proteins involving the DHN melanogenesis pathway are depicted from the initial acetyl-CoA or malonyl-CoA precursors through production of DHN melanin [4]. The Ssk2-Pbs2-Hog1 signalling cascade is a regulator of melanin biosynthesis in V. dahliae [14]. The transcription factor VdMcm1 and the polyketide chain shortening enzyme Vayg1 also modulate DHN melanogenesis. Our work identified several key genes that contribute to DHN melanin biosynthesis and that are regulated by VdCmr1. Some of these genes are found within the cluster enriched in DHN melanin biosynthetic genes within the V. dahliae genome. The non-melanin synthesis-related genes, up or downregulated during microsclerotial development [7], are regulated by VdCmr1 as demonstrated in this study; these genes VDAG_03079 (catalase) and VDAG_08741 VDECH (endochitinase, VDAG_08741) also reside outside of the gene cluster enriched in melanin biosynthetic genes. aVDAG_03665 may catalyse both T4HN and T3HN reductase steps based upon the strong homology of VDAG_03665 to the THR1 protein of Colletotrichum lagenarium, which can catalyse both T4HN and T3HN reductase steps [41].
  1 in total

1.  Loss of function of VdDrs2, a P4-ATPase, impairs the toxin secretion and microsclerotia formation, and decreases the pathogenicity of Verticillium dahliae.

Authors:  Hui Ren; Xianbi Li; Yujie Li; Mengjun Li; Jiyuan Sun; Fanlong Wang; Jianyan Zeng; Yang Chen; Lei Wang; Xingying Yan; Yanhua Fan; Dan Jin; Yan Pei
Journal:  Front Plant Sci       Date:  2022-08-22       Impact factor: 6.627

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.