| Literature DB >> 29722267 |
Concepción Núñez1, José Antonio Garrote2, Eduardo Arranz3, José Ramón Bilbao4, Fernando Fernández Bañares5, Juana Jiménez6, Teresa Perucho7, Eva Ruiz Casares7, Félix Sánchez-Valverde8, Juan I Serrano9.
Abstract
Coeliac disease (CD) is a chronic autoimmune enteropathy triggered by gluten and related prolamines in genetically predisposed individuals. Although CD is a polygenic disease, there is a strong association with genes of the human leukocyte antigen (HLA) region. Most patients present the HLA-DQ2 heterodimer, specifically the DQ2.5 isoform, which is present in around 90-96% of patients of European ancestry.Entities:
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Year: 2018 PMID： 29722267 DOI： 10.17235/reed.2018.5269/2017
Source DB: PubMed Journal: Rev Esp Enferm Dig ISSN： 1130-0108 Impact factor: 2.086