| Literature DB >> 29721935 |
Yuhong Wang1,2, Ammaji Rajala1,2, Raju V S Rajala3,4,5,6.
Abstract
Over the last few years, huge progress has been made in the understanding of molecular mechanisms underlying the pathogenesis of retinal degenerative diseases. Such knowledge has led to the development of gene therapy approaches to treat these devastating disorders. Non-viral gene delivery has been recognized as a prospective treatment for retinal degenerative diseases. In this review, we will summarize the constituent characteristics and recent applications of three representative nanoparticles (NPs) in ocular therapy.Entities:
Keywords: Blindness; Lipid nanoparticles; Metal-based nanoparticles; Nanoparticles; Non-viral vectors; Ocular diseases; Polymer-based nanoparticles; Retinal degeneration
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Year: 2018 PMID： 29721935 PMCID： PMC6417423 DOI： 10.1007/978-3-319-75402-4_15
Source DB: PubMed Journal: Adv Exp Med Biol ISSN： 0065-2598 Impact factor: 2.622