Literature DB >> 29718420

Long-term effect of a practice-based intervention (HAPPY AUDIT) aimed at reducing antibiotic prescribing in patients with respiratory tract infections.

Carl Llor1, Lars Bjerrum2, José M Molero3, Ana Moragas4, Beatriz González López-Valcárcel5, M José Monedero6, Manuel Gómez7, Marina Cid8, Juan de Dios Alcántara9, Josep M Cots10, Joana M Ribas11, Guillermo García12, Jesús Ortega13, Vicenta Pineda14, Gloria Guerra15, Susana Munuera16.   

Abstract

Objectives: Few studies have evaluated the long-term effects of educational interventions on antibiotic prescription and the results are controversial. This study was aimed at assessing the effect of a multifaceted practice-based intervention carried out 6 years earlier on current antibiotic prescription for respiratory tract infections (RTIs).
Methods: The 210 general practitioners (GPs) who completed the first two registrations in 2008 and 2009 were invited to participate in a third registration. The intervention held before the second registration consisted of discussion about the first registration of results, appropriate use of antibiotics for RTIs, patient brochures, a workshop and the provision of rapid tests. As in the previous registrations, GPs were instructed to complete a template for all the patients with RTIs during 15 working days in 2015. A new group of GPs from the same areas was also invited to participate and acted as controls. A multilevel logistic regression analysis was performed considering the prescription of antibiotics as the dependent variable.
Results: A total of 121 GPs included in the 2009 intervention (57.6%) and 117 control GPs registered 22 247 RTIs. On adjustment for covariables, compared with the antibiotic prescription observed just after the intervention, GPs assigned to intervention prescribed slightly more antibiotics 6 years later albeit without statistically significant differences (OR 1.08, 95% CI 0.89-1.31, P = 0.46), while GPs in the control group prescribed significantly more antibiotics (OR 2.74, 95% CI 2.09-3.59, P < 0.001). Conclusions: This study shows that a single multifaceted intervention continues to reduce antibiotic prescribing 6 years later.

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Year:  2018        PMID: 29718420     DOI: 10.1093/jac/dky137

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN: 0305-7453            Impact factor:   5.790


  7 in total

Review 1.  Evidence-Based Strategies in Using Persuasive Interventions to Optimize Antimicrobial Use in Healthcare: a Narrative Review.

Authors:  Jun Rong Jeffrey Neo; Jeff Niederdeppe; Ole Vielemeyer; Brandyn Lau; Michelle Demetres; Hessam Sadatsafavi
Journal:  J Med Syst       Date:  2020-02-10       Impact factor: 4.460

2.  Efficacy and safety of rapid tests to guide antibiotic prescriptions for sore throat.

Authors:  Jérémie F Cohen; Jean-Yves Pauchard; Nils Hjelm; Robert Cohen; Martin Chalumeau
Journal:  Cochrane Database Syst Rev       Date:  2020-06-04

3.  [Utilisation of first-line antibiotics six years after a multifaceted intervention].

Authors:  J M Molero; M Gómez; G Guerra; J D Alcántara; J Ortega; G García; V Pineda; S Munuera; M Cid; M J Monedero; J M Ribas; J M Cots; A Moragas; L Bjerrum; C Llor
Journal:  Rev Esp Quimioter       Date:  2018-11-05       Impact factor: 1.553

4.  General practitioners' opinions and perceptions about antibiotic use for respiratory tract infections in primary care.

Authors:  Ana Moragas; José M Molero; Lars Bjerrum; Carles Llor
Journal:  Aten Primaria       Date:  2019-03-26       Impact factor: 1.137

5.  Impact of a multifaceted intervention to improve antibiotic prescribing: a pragmatic cluster-randomised controlled trial.

Authors:  Adolfo Figueiras; Paula López-Vázquez; Cristian Gonzalez-Gonzalez; Juan Manuel Vázquez-Lago; María Piñeiro-Lamas; Ana López-Durán; Coro Sánchez; María Teresa Herdeiro; Maruxa Zapata-Cachafeiro
Journal:  Antimicrob Resist Infect Control       Date:  2020-12-07       Impact factor: 4.887

6.  Impact of educational training and C-reactive protein point-of-care testing on antibiotic prescribing in rural and urban family physician practices in Latvia: a randomised controlled intervention study.

Authors:  Zane Likopa; Anda Kivite-Urtane; Vija Silina; Jana Pavare
Journal:  BMC Pediatr       Date:  2022-09-21       Impact factor: 2.567

7.  Successful improvement of antibiotic prescribing at Primary Care in Andalusia following the implementation of an antimicrobial guide through multifaceted interventions: An interrupted time-series analysis.

Authors:  Rocío Fernández-Urrusuno; Carmen Marina Meseguer Barros; Regina Sandra Benavente Cantalejo; Elena Hevia; Carmen Serrano Martino; Aranzazu Irastorza Aldasoro; Juan Limón Mora; Antonio López Navas; Beatriz Pascual de la Pisa
Journal:  PLoS One       Date:  2020-05-15       Impact factor: 3.240

  7 in total

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