Literature DB >> 29718111

GenomicScores: seamless access to genomewide position-specific scores from R and Bioconductor.

Pau Puigdevall1, Robert Castelo1.   

Abstract

Summary: Genomewide position-specific scores, such as those estimating conservation, constraint, fitness or mutation tolerance, are ubiquitous in current genome analyses. The diversity of sources and formats of these scores, as well as their size, increase the burden to use them. We present GenomicScores, a Bioconductor package that provides efficient storage and seamless access of genomewide position-specific scores from R, facilitating their use in genome analysis workflows. Availability and implementation: GenomicScores is implemented in R and available at https://bioconductor.org/packages/GenomicScores under the open source 'Artistic-2.0' license. Supplementary information: Supplementary data are available at Bioinformatics online.

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Year:  2018        PMID: 29718111     DOI: 10.1093/bioinformatics/bty311

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  6 in total

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3.  Intrinsic transcriptomic sex differences in human endothelial cells at birth and in adults are associated with coronary artery disease targets.

Authors:  Robin J G Hartman; Daniek M C Kapteijn; Saskia Haitjema; Mireille N Bekker; Michal Mokry; Gerard Pasterkamp; Mete Civelek; Hester M den Ruijter
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4.  Low immunogenicity of common cancer hot spot mutations resulting in false immunogenic selection signals.

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5.  tRFTars: predicting the targets of tRNA-derived fragments.

Authors:  Qiong Xiao; Peng Gao; Xuanzhang Huang; Xiaowan Chen; Quan Chen; Xinger Lv; Yu Fu; Yongxi Song; Zhenning Wang
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6.  Conservation of Aging and Cancer Epigenetic Signatures across Human and Mouse.

Authors:  Raúl F Pérez; Juan Ramón Tejedor; Pablo Santamarina-Ojeda; Virginia López Martínez; Rocío G Urdinguio; Lucía Villamañán; Ana Paula Candiota; N Mí Vidal Sarró; Marta Barradas; Pablo Jose Fernandez-Marcos; Manuel Serrano; Agusín F Fernández; Mario F Fraga
Journal:  Mol Biol Evol       Date:  2021-07-29       Impact factor: 16.240

  6 in total

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