Literature DB >> 29717569

Intermediate Pilomyxoid Astrocytoma in the Cerebellum of a 5-Year-Old Boy.

Jin Sang Kil1, Kyung Hwa Lee2, Ki Seong Eom1, Tae Young Kim3.   

Abstract

Intermediate pilomyxoid tumors (IPTs) were defined by the presence of some features typical of pilomyxoid astrocytoma (PMA) in combination with features that could be considered more consistent with pilocytic astrocytoma (PA). PMA is rare in the cerebellum. And, IPT in the cerebellum is rarer than PMA. To our knowledge, only 2 reports have described IPT in the cerebellum. A 5-year-old boy had nausea and vomiting. Computed tomography revealed a large, round, low-density tumor in the cerebellar vermis area. On enhanced magnetic resonance imaging (MRI), the tumor showed inhomogeneous diffuse enhancement; the central portion showed homogenous enhancement, while the peripheral portion showed inhomogeneous enhancement. The patient underwent a midline suboccipital craniotomy, and gross total resection was performed. The tumor was gray-colored, rubbery hard, and severely hemorrhagic with a clear boundary. On pathologic examination, the combined features of both PA and PMA were retrospectively indicative of an IPT. The patient was symptom-free for 18 months, with no evidence of tumor recurrence on MRI. More observation and further studies on PMA and IPT are required to determine the most appropriate treatment for these tumors.
Copyright © 2018 The Korean Brain Tumor Society, The Korean Society for Neuro-Oncology, and The Korean Society for Pediatric Neuro-Oncology.

Entities:  

Keywords:  Cerebellum; Intermediate; Neoplasm; Pilomyxoid

Year:  2018        PMID: 29717569      PMCID: PMC5932298          DOI: 10.14791/btrt.2018.6.e6

Source DB:  PubMed          Journal:  Brain Tumor Res Treat        ISSN: 2288-2405


  12 in total

1.  Pediatric cerebellar pilomyxoid-spectrum astrocytomas.

Authors:  Jonathan A Forbes; Bret C Mobley; Thomas M O'Lynnger; Calvin M Cooper; Mahan Ghiassi; Rimal Hanif; Matthew M Pearson
Journal:  J Neurosurg Pediatr       Date:  2011-07       Impact factor: 2.375

Review 2.  The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary.

Authors:  David N Louis; Arie Perry; Guido Reifenberger; Andreas von Deimling; Dominique Figarella-Branger; Webster K Cavenee; Hiroko Ohgaki; Otmar D Wiestler; Paul Kleihues; David W Ellison
Journal:  Acta Neuropathol       Date:  2016-05-09       Impact factor: 17.088

3.  Pediatric astrocytomas with monomorphous pilomyxoid features and a less favorable outcome.

Authors:  T Tihan; P G Fisher; J L Kepner; C Godfraind; R D McComb; P T Goldthwaite; P C Burger
Journal:  J Neuropathol Exp Neurol       Date:  1999-10       Impact factor: 3.685

4.  Pilomyxoid astrocytoma of the cerebellum.

Authors:  Olufemi A Ajani; Ghanem Al Sulaiti; Issam Al Bozom
Journal:  J Neurosurg Pediatr       Date:  2011-05       Impact factor: 2.375

5.  Clinico-pathological feature of pilomyxoid astrocytomas: three case reports.

Authors:  Masaya Nagaishi; Hideaki Yokoo; Junko Hirato; Yuhei Yoshimoto; Yoichi Nakazato
Journal:  Neuropathology       Date:  2011-04       Impact factor: 1.906

6.  Pilocytic and pilomyxoid hypothalamic/chiasmatic astrocytomas.

Authors:  Ricardo J Komotar; Peter C Burger; Benjamin S Carson; Henry Brem; Alessandro Olivi; Patricia T Goldthwaite; Tarik Tihan
Journal:  Neurosurgery       Date:  2004-01       Impact factor: 4.654

7.  Pilocytic astrocytomas in children: prognostic factors--a retrospective study of 80 cases.

Authors:  Carla Fernandez; Dominique Figarella-Branger; Nadine Girard; Corinne Bouvier-Labit; Joanny Gouvernet; Armando Paz Paredes; Gabriel Lena
Journal:  Neurosurgery       Date:  2003-09       Impact factor: 4.654

8.  Newly codified glial neoplasms of the 2007 WHO Classification of Tumours of the Central Nervous System: angiocentric glioma, pilomyxoid astrocytoma and pituicytoma.

Authors:  Daniel J Brat; Bernd W Scheithauer; Gregory N Fuller; Tarik Tihan
Journal:  Brain Pathol       Date:  2007-07       Impact factor: 6.508

9.  Surgical and clinical aspects of cerebellar pilomyxoid-spectrum astrocytomas in children.

Authors:  Mohamed A El Beltagy; Mostafa M E Atteya; Alaa El-Haddad; Madiha Awad; Hala Taha; Mohamed Kamal; Sherif Abou El Naga
Journal:  Childs Nerv Syst       Date:  2014-02-05       Impact factor: 1.475

Review 10.  Significance of radical resection for pilomyxoid astrocytoma of the cerebellum: a case report and review of the literature.

Authors:  Atsushi Okano; Soichi Oya; Naoaki Fujisawa; Tsukasa Tsuchiya; Masahiro Indo; Takumi Nakamura; Han Soo Chang; Toru Matsui
Journal:  Childs Nerv Syst       Date:  2013-03-17       Impact factor: 1.475

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