Bilun Gemicioglu1, Hasan Bayram2, Arif Cimrin3, Oznur Abadoglu4, Aykut Cilli5, Esra Uzaslan6, Hakan Gunen7, Levent Akyildiz8, Mecit Suerdem9, Tevfik Ozlu10, Zeynep Misirligil11. 1. a Department of Pulmonary Diseases, Cerrahpasa Faculty of Medicine , Istanbul University , Istanbul , Turkey. 2. b Department of Pulmonary Diseases, Koç University , Medical School. 3. c Department of Pulmonary Diseases, Faculty of Medicine , Dokuz Eylul University , Izmir , Turkey. 4. d Department of Pulmonary Diseases, Faculty of Medicine , Cumhuriyet University , Sivas , Turkey. 5. e Department of Pulmonary Diseases, Faculty of Medicine , Akdeniz University , Antalya , Turkey. 6. f Department of Pulmonary Diseases, Faculty of Medicine , Uludag University , Bursa , Turkey. 7. g Department of Pulmonary Diseases , Sureyyapasa Pulmonary Diseases Hospital and Research Center , Istanbul , Turkey. 8. h Department of Pulmonary Diseases , Memorial Dicle Hospital , Diyarbakir , Turkey. 9. i Department of Pulmonary Diseases, Faculty of Medicine , Selcuk University , Konya , Turkey. 10. j Department of Pulmonary Diseases, Faculty of Medicine , Karadeniz Teknik University , Trabzon , Turkey. 11. k Department of Pulmonary Diseases, Faculty of Medicine , Ankara University , Ankara , Turkey.
Abstract
OBJECTIVE: This study aimed to evaluate the factors that affect asthma control and adherence to treatment in newly diagnosed elderly asthmatics in Turkey compared with younger patients. METHODS: This real-life prospective observational cohort study was conducted at 136 centers. A web-based questionnaire was administered to the patients who were followed up for 12 months. RESULTS: Analysis included 1037 young adult asthma patients (age <65 years) and 79 elderly asthma patients (age ≥65 years). The percentage of patients with total control in the elderly and young groups were 33.9% and 37.1% at visit 1, 20.0% and 42.1% (p = 0.012) at visit 2, and 50.0% and 49.8% at visit 3, respectively. Adherence to treatment was similar for both groups. Visit compliance was better in the elderly group than in the young group at visit 1 (72.2% vs. 60.8%, p = 0.045), visit 2 (51.9% vs. 34.9%, p = 0.002), and visit 3 (32.9% vs. 19.4%, p = 0.004). Adherence to treatment increased with asthma control in both groups (both p < 0.001) but decreased with the presence of gastritis/ulcer, gastroesophageal reflux, and coronary artery disease in the elderly. CONCLUSIONS: Asthma control and adherence to treatment were similar for the elderly and young asthma patients, though the follow-up rate was lower in young patients. The presence of gastritis/ulcer, gastroesophageal reflux and coronary artery disease had negative impacts on the adherence to treatment in elderly adult patients.
OBJECTIVE: This study aimed to evaluate the factors that affect asthma control and adherence to treatment in newly diagnosed elderly asthmatics in Turkey compared with younger patients. METHODS: This real-life prospective observational cohort study was conducted at 136 centers. A web-based questionnaire was administered to the patients who were followed up for 12 months. RESULTS: Analysis included 1037 young adult asthmapatients (age <65 years) and 79 elderly asthmapatients (age ≥65 years). The percentage of patients with total control in the elderly and young groups were 33.9% and 37.1% at visit 1, 20.0% and 42.1% (p = 0.012) at visit 2, and 50.0% and 49.8% at visit 3, respectively. Adherence to treatment was similar for both groups. Visit compliance was better in the elderly group than in the young group at visit 1 (72.2% vs. 60.8%, p = 0.045), visit 2 (51.9% vs. 34.9%, p = 0.002), and visit 3 (32.9% vs. 19.4%, p = 0.004). Adherence to treatment increased with asthma control in both groups (both p < 0.001) but decreased with the presence of gastritis/ulcer, gastroesophageal reflux, and coronary artery disease in the elderly. CONCLUSIONS:Asthma control and adherence to treatment were similar for the elderly and young asthmapatients, though the follow-up rate was lower in young patients. The presence of gastritis/ulcer, gastroesophageal reflux and coronary artery disease had negative impacts on the adherence to treatment in elderly adult patients.
Authors: Ayşe Arzu Yorgancıoğlu; Bilun Gemicioğlu; Cemal Cingi; Ömer Kalaycı; Ali Fuat Kalyoncu; Claus Bachert; Peter Hellings; Oliver Pfaar; Holger J Schünemann; Dana Wallace; Anna Bedbrook; Wienczyslawa Czarlewski; Jean Bousquet Journal: Turk Thorac J Date: 2020-03-01
Authors: Janette Yung; Sukhminder Osahan; Stephen M Friedman; Jiehui Li; James E Cone Journal: Int J Environ Res Public Health Date: 2019-05-30 Impact factor: 3.390