Literature DB >> 29713987

Low Rates of Dermatologic Care and Skin Cancer Screening Among Inflammatory Bowel Disease Patients.

Alyce Anderson1, Laura K Ferris2, Benjamin Click3, Claudia Ramos-Rivers3, Ioannis E Koutroubakis3, Jana G Hashash3, Michael Dunn3, Arthur Barrie3, Marc Schwartz3, Miguel Regueiro3, David G Binion4.   

Abstract

BACKGROUND: Dermatologic manifestations of inflammatory bowel disease (IBD) are common, and certain IBD medications increase the risk of skin cancer. AIMS: To define the rates of care and factors associated with dermatologic utilization with a focus on skin cancer screening.
METHODS: We utilized a prospective, natural history IBD research registry to evaluate all outpatient healthcare encounters from 2010 to 2016. Gastrointestinal, dermatologic and primary care visits per individual were identified. We calculated the proportion of patients obtaining care, categorized primary indications for dermatologic visits, determined the incidence of melanoma and non-melanoma skin cancers, and used logistic regression to determine factors associated with dermatology utilization.
RESULTS: Of the 2127 IBD patients included, 452 (21.3%) utilized dermatology over the study period, and 55 (2.6%) had a total body skin examination at least once. The 452 patients incurred 1633 dermatology clinic visits, 278 dermatologic procedures, and 1108 dermatology telephone encounters. The most frequent indication was contact dermatitis or dermatitis. Factors associated with dermatology use were family history of skin cancer, employment, systemic steroids, longer disease duration, emergency room use, and the number of IBD-related clinic visits. Between 8.3 and 11% of IBD patients recommended for skin cancer screening visited dermatology each year, and the resulting incidence of non-melanoma skin cancer was 35.4/10,000 [95% CI 23.3-51.5] and melanoma was 6.56/10,000 [95% CI 2.1-15.3].
CONCLUSIONS: Less than one in ten IBD patients obtain dermatologic care. Given the increased risk of skin cancers among IBD patients, an emphasis on education, prevention, and screening merits attention.

Entities:  

Keywords:  Dermatologic manifestations; Dermatology; Inflammatory bowel disease; Preventative medicine; Skin cancer screening

Mesh:

Year:  2018        PMID: 29713987     DOI: 10.1007/s10620-018-5056-x

Source DB:  PubMed          Journal:  Dig Dis Sci        ISSN: 0163-2116            Impact factor:   3.199


  41 in total

1.  The First European Evidence-based Consensus on Extra-intestinal Manifestations in Inflammatory Bowel Disease.

Authors:  Marcus Harbord; Vito Annese; Stephan R Vavricka; Matthieu Allez; Manuel Barreiro-de Acosta; Kirsten Muri Boberg; Johan Burisch; Martine De Vos; Anne-Marie De Vries; Andrew D Dick; Pascal Juillerat; Tom H Karlsen; Ioannis Koutroubakis; Peter L Lakatos; Tim Orchard; Pavol Papay; Tim Raine; Max Reinshagen; Diamant Thaci; Herbert Tilg; Franck Carbonnel
Journal:  J Crohns Colitis       Date:  2015-11-27       Impact factor: 9.071

2.  Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology.

Authors:  Mark S Silverberg; Jack Satsangi; Tariq Ahmad; Ian D R Arnott; Charles N Bernstein; Steven R Brant; Renzo Caprilli; Jean-Frédéric Colombel; Christoph Gasche; Karel Geboes; Derek P Jewell; Amir Karban; Edward V Loftus; A Salvador Peña; Robert H Riddell; David B Sachar; Stefan Schreiber; A Hillary Steinhart; Stephan R Targan; Severine Vermeire; B F Warren
Journal:  Can J Gastroenterol       Date:  2005-09       Impact factor: 3.522

3.  Melanoma and non-melanoma skin cancer in inflammatory bowel disease patients following tumor necrosis factor-α inhibitor monotherapy and in combination with thiopurines: analysis of the Food and Drug Administration Adverse Event Reporting System.

Authors:  Michael R McKenna; Derrick J Stobaugh; Parakkal Deepak
Journal:  J Gastrointestin Liver Dis       Date:  2014-09       Impact factor: 2.008

4.  Increasing capacity for skin surveillance in a transplant review clinic.

Authors:  Faisal R Ali; Venura Samarasinghe; Sheila A Russell; John T Lear
Journal:  Transplantation       Date:  2014-04-27       Impact factor: 4.939

5.  Incidence of skin cancer in 5356 patients following organ transplantation.

Authors:  B Lindelöf; B Sigurgeirsson; H Gäbel; R S Stern
Journal:  Br J Dermatol       Date:  2000-09       Impact factor: 9.302

6.  Skin cancer evaluation in transplant patients: a physician opinion survey with recommendations.

Authors:  Amanda Lloyd; Goran Klintmalm; Huanying Qin; Alan Menter
Journal:  Clin Transplant       Date:  2014-12-20       Impact factor: 2.863

7.  Methotrexate induces clinical and histologic remission in patients with refractory inflammatory bowel disease.

Authors:  R A Kozarek; D J Patterson; M D Gelfand; V A Botoman; T J Ball; K R Wilske
Journal:  Ann Intern Med       Date:  1989-03-01       Impact factor: 25.391

8.  Risk of melanoma and non-melanoma skin cancer in ulcerative colitis patients treated with thiopurines: a nationwide retrospective cohort.

Authors:  Ali M Abbas; Rawaa M Almukhtar; Edward V Loftus; Gary R Lichtenstein; Nabeel Khan
Journal:  Am J Gastroenterol       Date:  2014-09-23       Impact factor: 10.864

Review 9.  Inflammatory bowel disease is associated with an increased risk of melanoma: a systematic review and meta-analysis.

Authors:  Siddharth Singh; Sajan Jiv Singh Nagpal; Mohammad H Murad; Siddhant Yadav; Sunanda V Kane; Darrell S Pardi; Jayant A Talwalkar; Edward V Loftus
Journal:  Clin Gastroenterol Hepatol       Date:  2013-05-02       Impact factor: 11.382

10.  Skin manifestations of inflammatory bowel disease.

Authors:  Brian L Huang; Stephanie Chandra; David Quan Shih
Journal:  Front Physiol       Date:  2012-02-06       Impact factor: 4.566

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  5 in total

1.  More Skin in the Game: Screening for Skin Cancer in IBD Patients.

Authors:  Seema A Patil; Raymond K Cross
Journal:  Dig Dis Sci       Date:  2018-10       Impact factor: 3.199

2.  Therapy Patterns and Surveillance Measures of Inflammatory Bowel Disease Patients beyond Disease-Related Hospitalization: A Claims-Based Cohort Study.

Authors:  Caroline Bähler; Beat Brüngger; Eva Blozik; Stephan R Vavricka; Alain M Schoepfer
Journal:  Inflamm Intest Dis       Date:  2022-04-27

Review 3.  Risk of Developing Melanoma With Systemic Agents Used to Treat Psoriasis: A Review of the Literature.

Authors:  Amy Semaka; Thomas G Salopek
Journal:  J Cutan Med Surg       Date:  2021-08-15       Impact factor: 2.092

Review 4.  Solid extraintestinal malignancies in patients with inflammatory bowel disease.

Authors:  Anastasia Mala; Kalliopi Foteinogiannopoulou; Ioannis E Koutroubakis
Journal:  World J Gastrointest Oncol       Date:  2021-12-15

Review 5.  Cutaneous Manifestations in Biological-Treated Inflammatory Bowel Disease Patients: A Narrative Review.

Authors:  Jo L W Lambert; Sofie De Schepper; Reinhart Speeckaert
Journal:  J Clin Med       Date:  2021-03-03       Impact factor: 4.241

  5 in total

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