Literature DB >> 2971356

Regional distribution of immunoreactive brain natriuretic peptide in porcine brain and spinal cord.

S Ueda1, N Minamino, T Sudoh, K Kangawa, H Matsuo.   

Abstract

In order to elucidate the physiological functions of brain natriuretic peptide (BNP), radioimmunoassay for BNP was established and regional distribution of BNP in porcine brain and spinal cord was investigated. The concentration of immunoreactive (ir-) BNP in porcine whole brain was estimated to be 0.63 pmol/g, 13 times higher than that of ir-atrial natriuretic peptide (ANP). Highest concentrations of ir-BNP were found in the medulla-pons, striatum, and spinal cord. Medium concentration was noted in the hypothalamus. This distribution of ir-BNP in porcine brain was found to be different from that of ir-ANP simultaneously measured. Furthermore, BNP and BNP-32 were identified as two major forms of ir-BNP in porcine brain.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 2971356     DOI： 10.1016/s0006-291x(88)80556-4

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  6 in total

1.  Atrial natriuretic factor-like immunoreactivity in spinal cord and in primary sensory neurons of spinal and trigeminal ganglia of guinea-pig: correlation with tachykinin immunoreactivity.

Authors:  D Nohr; E Weihe; H J Zentel; R M Arendt
Journal:  Cell Tissue Res       Date:  1989-11       Impact factor: 5.249

2.  Stimulatory effects of brain natriuretic peptide on cyclic GMP accumulation and tyrosine hydroxylase activity in cultured bovine adrenal medullary cells.

Authors:  N Yanagihara; M Okazaki; T Terao; Y Uezono; A Wada; F Izumi
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1991-03       Impact factor: 3.000

3.  Comparison of renal function under deliberate hypotension during epidural plus light-enflurane anesthesia and during enflurane anesthesia.

Authors:  Naoto Nagata; Mayumi Takasaki; Gohtaro Yoshikawa; Tadashi Agune; Michiyo Takeshita; Naoto Minamino
Journal:  J Anesth       Date:  1996-06       Impact factor: 2.078

4.  The hydrolysis of brain and atrial natriuretic peptides by porcine choroid plexus is attributable to endopeptidase-24.11.

Authors:  A Bourne; A J Kenny
Journal:  Biochem J       Date:  1990-10-15       Impact factor: 3.857

Review 5.  The Interplay between cGMP and Calcium Signaling in Alzheimer's Disease.

Authors:  Aileen Jehle; Olga Garaschuk
Journal:  Int J Mol Sci       Date:  2022-06-24       Impact factor: 6.208

6.  Localization of Brain Natriuretic Peptide Immunoreactivity in Rat Spinal Cord.

Authors:  Essam M Abdelalim; Jean-Pierre Bellier; Ikuo Tooyama
Journal:  Front Neuroanat       Date:  2016-12-02       Impact factor: 3.856
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.