| Literature DB >> 29712486 |
Mario Petrillo1, Francesca Patella2, Filippo Pesapane2, Matteo B Suter3, Anna M Ierardi1, Salvatore A Angileri1, Chiara Floridi4, Massimo de Filippo5, Gianpaolo Carrafiello1.
Abstract
This review focuses upon interactions and potential therapeutic targets in the 'vicious cycle' between hypoxia and neoangiogenesis following treatment of hepatocellular carcinoma with transarterial loco-regional therapies. Biomarkers correlated with angiogenesis have been studied by many authors as prognostic determinants following transarterial intrahepatic therapy. According to these results future therapies directed toward specific factors related to angiogenesis could play a significant role in preventing local tumor recurrence and remote metastasis.Entities:
Keywords: HCC; TACE; TAE; TARE; VEGF; embolotherapy; hypoxia; individualized treatment; neoangiogenesis; sorafenib
Mesh:
Year: 2018 PMID: 29712486 DOI: 10.2217/fon-2017-0739
Source DB: PubMed Journal: Future Oncol ISSN: 1479-6694 Impact factor: 3.404