| Literature DB >> 29712014 |
Stephen D Fuerstenau1, W Henry Benner2, John J Thomas3, Christophe Brugidou3, Brian Bothner3, Gary Siuzdak3.
Abstract
The simultaneous measurement of the time-of-flight and the number of charges on each electrosprayed ion provides a new way to determine the mass of a whole intact virus. The weights of an icosahedral virus (rice yellow mottle virus) consisting of a single-stranded RNA surrounded by a homogeneous protein shell with a mass of 6.5×106 Da, and a rod-shaped RNA virus (tobacco mosaic virus) with a mass of 40.5×106 Da were measured with this technique.Entities:
Keywords: RNA structures; mass spectrometry; noncovalent interactions; viruses
Year: 2001 PMID: 29712014 DOI: 10.1002/1521-3773(20010202)40:3<541::AID-ANIE541>3.0.CO;2-K
Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN: 1433-7851 Impact factor: 15.336