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Literature DB >> 29711719

The Vancomycin Group of Antibiotics and the Fight against Resistant Bacteria.

Abstract

A last line of defence against "superbugs" are the vancomycin group antibiotics. This review describes the determination of their mode of action, and a mechanism of resistance to them. Remarkably, this mechanism of resistance can be overcome without directly modifying the binding site of the antibiotics for the cell-wall precursors of pathogenic bacteria. © 1999 WILEY-VCH Verlag GmbH, Weinheim, Fed. Rep. of Germany.

Entities: Chemical

Keywords: Antibiotics; Cooperative effects; Dimerizations; Resistant bacteria; Vancomycin

Year: 1999 PMID： 29711719 DOI： 10.1002/(SICI)1521-3773(19990503)38:9<1172::AID-ANIE1172>3.0.CO;2-C

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

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Cited

28 in total

1. Vancomycin C-Terminus Guanidine Modifications and Further Insights into an Added Mechanism of Action Imparted by a Peripheral Structural Modification.

Authors: Zhi-Chen Wu; Michael D Cameron; Dale L Boger
Journal: ACS Infect Dis Date: 2020-07-14 Impact factor: 5.084

2. Thieno[2,3-d]pyrimidinedione derivatives as antibacterial agents.

Authors: Mahender B Dewal; Amit S Wani; Celine Vidaillac; David Oupický; Michael J Rybak; Steven M Firestine
Journal: Eur J Med Chem Date: 2012-02-25 Impact factor: 6.514

3. A stepwise dechlorination/cross-coupling strategy to diversify the vancomycin 'in-chloride'.

Authors: Tyler J Wadzinski; Katherine D Gea; Scott J Miller
Journal: Bioorg Med Chem Lett Date: 2015-12-11 Impact factor: 2.823

Review 4. Natural Products in the "Marketplace": Interfacing Synthesis and Biology.

Authors: Benjamin J Huffman; Ryan A Shenvi
Journal: J Am Chem Soc Date: 2019-02-13 Impact factor: 15.419

5. Host-guest chemistry of the peptidoglycan.

Authors: Jed F Fisher; Shahriar Mobashery
Journal: J Med Chem Date: 2010-07-08 Impact factor: 7.446

6. N-Terminus Alkylation of Vancomycin: Ligand Binding Affinity, Antimicrobial Activity, and Site-Specific Nature of Quaternary Trimethylammonium Salt Modification.

Authors: Zhi-Chen Wu; Nicholas A Isley; Dale L Boger
Journal: ACS Infect Dis Date: 2018-08-08 Impact factor: 5.084

The Vancomycin Group of Antibiotics and the Fight against Resistant Bacteria.

1. Vancomycin C-Terminus Guanidine Modifications and Further Insights into an Added Mechanism of Action Imparted by a Peripheral Structural Modification.

2. Thieno[2,3-d]pyrimidinedione derivatives as antibacterial agents.

3. A stepwise dechlorination/cross-coupling strategy to diversify the vancomycin 'in-chloride'.

Review 4. Natural Products in the "Marketplace": Interfacing Synthesis and Biology.

5. Host-guest chemistry of the peptidoglycan.

6. N-Terminus Alkylation of Vancomycin: Ligand Binding Affinity, Antimicrobial Activity, and Site-Specific Nature of Quaternary Trimethylammonium Salt Modification.

7. Next-Generation Total Synthesis of Vancomycin.

8. Synthesis and binding studies of two new macrocyclic receptors for the stereoselective recognition of dipeptides.

Review 9. Recognition of chiral carboxylic anions by artificial receptors.

10. Preparation of novel selenopenams by intramolecular homolytic substitution.