Literature DB >> 29711637

The Chemistry and Biology of Alkannin, Shikonin, and Related Naphthazarin Natural Products.

Vassilios P Papageorgiou1, Andreana N Assimopoulou1, Elias A Couladouros2, David Hepworth3, K C Nicolaou3.   

Abstract

Wound healing properties of plant extracts that contain the naphthoquinone natural products alkannin (1) and shikonin (2) have been known for many centuries. More recently, the biological properties of 1, 2, and related derivatives have been demonstrated experimentally, and their production both by cell cultures and chemical synthesis has been studied extensively. © 1999 WILEY-VCH Verlag GmbH, Weinheim, Fed. Rep. of Germany.

Entities:  

Keywords:  Bioorganic chemistry; Natural products; Phytochemistry; Quinones; Wound healing

Year:  1999        PMID： 29711637     DOI： 10.1002/(SICI)1521-3773(19990201)38:3<270::AID-ANIE270>3.0.CO;2-0

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  52 in total

1.  Isolation and chemopreventive evaluation of novel naphthoquinone compounds from Alkanna tinctoria.

Authors:  Nguyen Huu Tung; Guang-Jian Du; Chun-Su Yuan; Yukihiro Shoyama; Chong-Zhi Wang
Journal:  Anticancer Drugs       Date:  2013-11       Impact factor: 2.248

2.  Effectiveness of a hydroxynaphthoquinone fraction from Arnebia euchroma in rats with experimental colitis.

Authors:  Hua-Ying Fan; Zi-Liang Zhang; Ke Liu; Ming-Yan Yang; Wei-Hong Lv; Xin Che; Hui Xu; Wei-Wei Song
Journal:  World J Gastroenterol       Date:  2013-12-28       Impact factor: 5.742

3.  CYP76B74 Catalyzes the 3''-Hydroxylation of Geranylhydroquinone in Shikonin Biosynthesis.

Authors:  Sheng Wang; Ruishan Wang; Tan Liu; Chaogeng Lv; Jiuwen Liang; Chuanzhi Kang; Liangyun Zhou; Juan Guo; Guanghong Cui; Yan Zhang; Daniele Werck-Reichhart; Lanping Guo; Luqi Huang
Journal:  Plant Physiol       Date:  2018-11-29       Impact factor: 8.340

4.  Two BAHD Acyltransferases Catalyze the Last Step in the Shikonin/Alkannin Biosynthetic Pathway.

Authors:  Haruka Oshikiri; Bunta Watanabe; Hirobumi Yamamoto; Kazufumi Yazaki; Kojiro Takanashi
Journal:  Plant Physiol       Date:  2020-07-29       Impact factor: 8.340

Review 5.  Anticancer agents that counteract tumor glycolysis.

Authors:  Carlotta Granchi; Filippo Minutolo
Journal:  ChemMedChem       Date:  2012-06-08       Impact factor: 3.466

6.  An efficient in vitro shoot regeneration from immature inflorescence and ex vitro rooting of Arnebia hispidissima (Lehm). DC. - A red dye (Alkannin) yielding plant.

Authors:  Mahendra Phulwaria; N S Shekhawat
Journal:  Physiol Mol Biol Plants       Date:  2013-07

7.  Shikonin, a component of chinese herbal medicine, inhibits chemokine receptor function and suppresses human immunodeficiency virus type 1.

Authors:  Xin Chen; Lu Yang; Ning Zhang; Jim A Turpin; Robert W Buckheit; Clay Osterling; Joost J Oppenheim; O M Zack Howard
Journal:  Antimicrob Agents Chemother       Date:  2003-09       Impact factor: 5.191

8.  Development of antibiotic activity profile screening for the classification and discovery of natural product antibiotics.

Authors:  Weng Ruh Wong; Allen G Oliver; Roger G Linington
Journal:  Chem Biol       Date:  2012-11-21

9.  Synthesis of some NH- and NH,S- substituted 1,4-quinones.

Authors:  Ayşecik Kaçmaz
Journal:  Turk J Chem       Date:  2021-04-28       Impact factor: 1.239

10.  A Simple Isocratic High-perfomance Liquid Chromatography Method for the Simultaneous Determination of Shikonin Derivatives in Some Echium Species Growing Wild in Turkey.

Authors:  Nuraniye Eruygur
Journal:  Turk J Pharm Sci       Date:  2018-04-02
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