Literature DB >> 29711574

Strobilurins: Evolution of a New Class of Active Substances.

Hubert Sauter1, Wolfgang Steglich2, Timm Anke3.   

Abstract

A fungus that grows on pinecones yields a compound with antifungal activity that has become the natural model for a significant innovation in crop protection. Variation and optimization of the lead structure of strobilurin A (1) and selection of derivatives which fulfill all practical requirements, for example, kresoxim-methyl (2), led to an exciting and pan-industrial competition for the development of the strobilurines as a new, highly active, and broadly applicable class of fungicides-a fascinating success story. © 1999 WILEY-VCH Verlag GmbH, Weinheim, Fed. Rep. of Germany.

Entities:  

Keywords:  Active substance research; Fungicides; Natural products; Strobilurins; Structure-activity relationships

Year:  1999        PMID： 29711574     DOI： 10.1002/(SICI)1521-3773(19990517)38:10<1328::AID-ANIE1328>3.0.CO;2-1

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  25 in total

1.  Latest Research Trends in Agrochemical Fungicides: Any Learnings for Pharmaceutical Antifungals?

Authors:  Clemens Lamberth
Journal:  ACS Med Chem Lett       Date:  2022-05-16       Impact factor: 4.632

2.  Natural Protein Kinase Inhibitors, Staurosporine, and Chelerythrine Suppress Wheat Blast Disease Caused by Magnaporthe oryzae Triticum.

Authors:  Moutoshi Chakraborty; S M Fajle Rabby; Dipali Rani Gupta; Mahfuzur Rahman; Sanjoy Kumar Paul; Nur Uddin Mahmud; Abdullah Al Mahbub Rahat; Ljupcho Jankuloski; Tofazzal Islam
Journal:  Microorganisms       Date:  2022-06-09

3.  A strobilurin fungicide enhances the resistance of tobacco against tobacco mosaic virus and Pseudomonas syringae pv tabaci.

Authors:  Stefan Herms; Kai Seehaus; Harald Koehle; Uwe Conrath
Journal:  Plant Physiol       Date:  2002-09       Impact factor: 8.340

4.  Subnanomolar inhibitor of cytochrome bc1 complex designed by optimizing interaction with conformationally flexible residues.

Authors:  Pei-Liang Zhao; Le Wang; Xiao-Lei Zhu; Xiaoqin Huang; Chang-Guo Zhan; Jia-Wei Wu; Guang-Fu Yang
Journal:  J Am Chem Soc       Date:  2010-01-13       Impact factor: 15.419

Review 5.  Structural basis of resistance to anti-cytochrome bc₁ complex inhibitors: implication for drug improvement.

Authors:  Lothar Esser; Chang-An Yu; Di Xia
Journal:  Curr Pharm Des       Date:  2014       Impact factor: 3.116

6.  Inhibitory Effects of Linear Lipopeptides From a Marine Bacillus subtilis on the Wheat Blast Fungus Magnaporthe oryzae Triticum.

Authors:  Moutoshi Chakraborty; Nur Uddin Mahmud; Dipali Rani Gupta; Fakir Shahidullah Tareq; Hee Jae Shin; Tofazzal Islam
Journal:  Front Microbiol       Date:  2020-04-30       Impact factor: 5.640

7.  Investigations into the biosynthesis of the antifungal strobilurins.

Authors:  Zafar Iqbal; Li-Chen Han; Anna M Soares-Sello; Risa Nofiani; Gerald Thormann; Axel Zeeck; Russell J Cox; Christine L Willis; Thomas J Simpson
Journal:  Org Biomol Chem       Date:  2018-08-01       Impact factor: 3.876

8.  Synthesis and Antibacterial Evaluation of New Sulfone Derivatives Containing 2-Aroxymethyl-1,3,4-Oxadiazole/Thiadiazole Moiety.

Authors:  Shihu Su; Xia Zhou; Guoping Liao; Puying Qi; Linhong Jin
Journal:  Molecules       Date:  2016-12-31       Impact factor: 4.411

9.  Design, synthesis, crystal structure and fungicidal activity of (E)-5-(methoxyimino)-3,5-dihydrobenzo[e][1,2]oxazepin-4(1H)-one analogues.

Authors:  Dongyan Yang; Chuan Wan; MengMeng He; Chuanliang Che; Yumei Xiao; Bin Fu; Zhaohai Qin
Journal:  Medchemcomm       Date:  2017-03-08       Impact factor: 3.597

10.  Cross-resistance to strobilurin fungicides in mitochondrial and nuclear mutants of Saccharomyces cerevisiae.

Authors:  M Hnátová; Y Gbelská; M Obernauerová; V Subíková; J Subík
Journal:  Folia Microbiol (Praha)       Date:  2003       Impact factor: 2.629
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