Literature DB >> 29711174

The Catalytic Enantioselective Construction of Molecules with Quaternary Carbon Stereocenters.

Elias J Corey1, Angel Guzman-Perez1.   

Abstract

A long-standing challenge to synthesis can now be met through the use of new and powerful catalytic asymmetric reactions for the assembly of complex chiral molecules with quaternary stereocenters from achiral building blocks. The reaction sequence shown below is just one example discussed in this review. © 1998 WILEY-VCH Verlag GmbH, Weinheim, Fed. Rep. of Germany.

Entities:  

Keywords:  Asymmetric catalysis; Chirality; Enantioselective addition; Quaternary stereocenters; Total synthesis

Year:  1998        PMID： 29711174     DOI： 10.1002/(SICI)1521-3773(19980302)37:4<388::AID-ANIE388>3.0.CO;2-V

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  42 in total

1.  Total synthesis of asperazine.

Authors:  S P Govek; L E Overman
Journal:  J Am Chem Soc       Date:  2001-09-26       Impact factor: 15.419

2.  High-Throughput Screening of the Asymmetric Decarboxylative Alkylation Reaction of Enolate-Stabilized Enol Carbonates.

Authors:  Nolan T McDougal; Scott C Virgil; Brian M Stoltz
Journal:  Synlett       Date:  2010-01-01       Impact factor: 2.454

3.  Asymmetric hetero Diels-Alder route to quaternary carbon centers: synthesis of (-)-malyngolide.

Authors:  Arun K Ghosh; Michio Shirai
Journal:  Tetrahedron Lett       Date:  2001-08-09       Impact factor: 2.415

4.  Formation of the BC ring system of upenamide via a Staudinger/aza-Wittig reaction.

Authors:  Zhushou Luo; Katherine Peplowski; Gary A Sulikowski
Journal:  Org Lett       Date:  2007-11-01       Impact factor: 6.005

5.  Stereoselective construction of quaternary carbon centers by three component coupling reactions.

Authors:  Arun K Ghosh; Reiko Kawahama; Donald Wink
Journal:  Tetrahedron Lett       Date:  2000-11-01       Impact factor: 2.415

6.  Reaction Mechanism, Origins of Enantioselectivity, and Reactivity Trends in Asymmetric Allylic Alkylation: A Comprehensive Quantum Mechanics Investigation of a C(sp3)-C(sp3) Cross-Coupling.

Authors:  Alexander Q Cusumano; Brian M Stoltz; William A Goddard
Journal:  J Am Chem Soc       Date:  2020-07-30       Impact factor: 15.419

7.  Enantioselective Synthesis of Acyclic α-Quaternary Carboxylic Acid Derivatives through Iridium-Catalyzed Allylic Alkylation.

Authors:  Samantha E Shockley; J Caleb Hethcox; Brian M Stoltz
Journal:  Angew Chem Int Ed Engl       Date:  2017-08-09       Impact factor: 15.336

8.  Asymmetric Synthesis of All-Carbon Quaternary Spirocycles via a Catalytic Enantioselective Allylic Alkylation Strategy.

Authors:  Samantha E Shockley; J Caleb Hethcox; Brian M Stoltz
Journal:  Tetrahedron Lett       Date:  2017-07-05       Impact factor: 2.415

9.  Enantioselective Synthesis of Vicinal All-Carbon Quaternary Centers via Iridium-Catalyzed Allylic Alkylation.

Authors:  J Caleb Hethcox; Samantha E Shockley; Brian M Stoltz
Journal:  Angew Chem Int Ed Engl       Date:  2018-06-11       Impact factor: 15.336

10.  Tunable Phosphoramidite Ligands for Asymmetric Hydrovinylation: Ligands par excellence for Generation of All-Carbon Quaternary Centers.

Authors:  Craig R Smith; Hwan Jung Lim; Aibin Zhang; T V Rajanbabu
Journal:  Synthesis (Stuttg)       Date:  2009-01-01       Impact factor: 3.157
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