| Literature DB >> 29711151 |
Abstract
Carbenoid, electrophilic and carbanionic, nucleophilic character is shown by compounds 1, which bear a lithium atom and an electronegative element X as leaving group at the vinyl carbon center. Now that structural investigations have contributed significantly to their understanding, these ambiphilic, thermally unstable compounds are increasingly being used as reagents for synthetic purposes. © 1998 WILEY-VCH Verlag GmbH, Weinheim, Fed. Rep. of Germany.Entities:
Keywords: Asymmetric synthesis; Lithium; Nucleophilic additions; Synthetic methods; Umpolung
Year: 1998 PMID： 29711151 DOI： 10.1002/(SICI)1521-3773(19980302)37:4<430::AID-ANIE430>3.0.CO;2-5
Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336