Literature DB >> 29710982

Sphingolipids-Their Metabolic Pathways and the Pathobiochemistry of Neurodegenerative Diseases.

Thomas Kolter1, Konrad Sandhoff1.   

Abstract

Glycolipids such as ganglioside GM1 are involved in the building of carbohydrate layers on the surface of living cells. The investigation of the metabolism of this class of compounds gives insight into human diseases, novel signal transduction processes, and the epidermal water permeability barrier. © 1999 WILEY-VCH Verlag GmbH, Weinheim, Fed. Rep. of Germany.

Entities:  

Keywords:  Diseases; Enzyme inhibitors; Glycolipids; Glycosidases; Sphingolipids

Year:  1999        PMID： 29710982     DOI： 10.1002/(SICI)1521-3773(19990601)38:11<1532::AID-ANIE1532>3.0.CO;2-U

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  19 in total

1.  Ionizing radiations increase the activity of the cell surface glycohydrolases and the plasma membrane ceramide content.

Authors:  Massimo Aureli; Rosaria Bassi; Alessandro Prinetti; Elena Chiricozzi; Brigida Pappalardi; Vanna Chigorno; Nadia Di Muzio; Nicoletta Loberto; Sandro Sonnino
Journal:  Glycoconj J       Date:  2012-05-17       Impact factor: 2.916

2.  Membrane lipids regulate ganglioside GM2 catabolism and GM2 activator protein activity.

Authors:  Susi Anheuser; Bernadette Breiden; Günter Schwarzmann; Konrad Sandhoff
Journal:  J Lipid Res       Date:  2015-07-14       Impact factor: 5.922

3.  Renal sulfatides: sphingoid base-dependent localization and region-specific compensation of CerS2-dysfunction.

Authors:  Christian Marsching; Mariona Rabionet; Daniel Mathow; Richard Jennemann; Christiane Kremser; Stefan Porubsky; Christian Bolenz; Klaus Willecke; Hermann-Josef Gröne; Carsten Hopf; Roger Sandhoff
Journal:  J Lipid Res       Date:  2014-09-29       Impact factor: 5.922

4.  1-O-acylceramides are natural components of human and mouse epidermis.

Authors:  Mariona Rabionet; Aline Bayerle; Christian Marsching; Richard Jennemann; Hermann-Josef Gröne; Yildiz Yildiz; Dagmar Wachten; Walter Shaw; James A Shayman; Roger Sandhoff
Journal:  J Lipid Res       Date:  2013-09-27       Impact factor: 5.922

5.  Diastereomer-specific quantification of bioactive hexosylceramides from bacteria and mammals.

Authors:  Johanna von Gerichten; Kerstin Schlosser; Dominic Lamprecht; Ivan Morace; Matthias Eckhardt; Dagmar Wachten; Richard Jennemann; Hermann-Josef Gröne; Matthias Mack; Roger Sandhoff
Journal:  J Lipid Res       Date:  2017-04-03       Impact factor: 5.922

6.  Role of endosomal membrane lipids and NPC2 in cholesterol transfer and membrane fusion.

Authors:  Misbaudeen Abdul-Hammed; Bernadette Breiden; Matthew A Adebayo; Jonathan O Babalola; Günter Schwarzmann; Konrad Sandhoff
Journal:  J Lipid Res       Date:  2010-02-23       Impact factor: 5.922

7.  Ablation of neuronal ceramide synthase 1 in mice decreases ganglioside levels and expression of myelin-associated glycoprotein in oligodendrocytes.

Authors:  Christina Ginkel; Dieter Hartmann; Katharina vom Dorp; Armin Zlomuzica; Hany Farwanah; Matthias Eckhardt; Roger Sandhoff; Joachim Degen; Mariona Rabionet; Ekrem Dere; Peter Dörmann; Konrad Sandhoff; Klaus Willecke
Journal:  J Biol Chem       Date:  2012-10-16       Impact factor: 5.157

8.  Male germ cells require polyenoic sphingolipids with complex glycosylation for completion of meiosis: a link to ceramide synthase-3.

Authors:  Mariona Rabionet; Aarnoud C van der Spoel; Chia-Chen Chuang; Benita von Tümpling-Radosta; Manja Litjens; Diane Bouwmeester; Christina C Hellbusch; Christian Körner; Herbert Wiegandt; Karin Gorgas; Frances M Platt; Hermann-Josef Gröne; Roger Sandhoff
Journal:  J Biol Chem       Date:  2008-02-27       Impact factor: 5.157

9.  Adult ceramide synthase 2 (CERS2)-deficient mice exhibit myelin sheath defects, cerebellar degeneration, and hepatocarcinomas.

Authors:  Silke Imgrund; Dieter Hartmann; Hany Farwanah; Matthias Eckhardt; Roger Sandhoff; Joachim Degen; Volkmar Gieselmann; Konrad Sandhoff; Klaus Willecke
Journal:  J Biol Chem       Date:  2009-09-30       Impact factor: 5.157

Review 10.  A class of plant glycosyltransferases involved in cellular homeostasis.

Authors:  Eng-Kiat Lim; Dianna J Bowles
Journal:  EMBO J       Date:  2004-07-08       Impact factor: 11.598
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