| Literature DB >> 29710539 |
Wei Song1, Dong Yan2, Tianshu Wei1, Qiang Liu1, Xia Zhou3, Ju Liu4.
Abstract
Angiogenesis is crucial for tumor growth and metastasis. Recent studies revealed that tumor cells promote angiogenesis by secreting extracellular vesicles, which can be captured by endothelial cells. These tumor-derived extracellular vesicles carry microRNAs, long non-coding RNAs, and proteins, which activate pro-angiogenic signaling in endothelial cells. In this review, we will summarize the roles of tumor-derived extracellular vesicles in angiogenesis and the underlying molecular mechanisms.Entities:
Keywords: Angiogenesis; Endothelial cells; Extracellular vesicles
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Year: 2018 PMID: 29710539 DOI: 10.1016/j.biopha.2018.03.148
Source DB: PubMed Journal: Biomed Pharmacother ISSN: 0753-3322 Impact factor: 6.529