M El Amrani1, M Fulbert2, X Lenne3, G Clément3, E Drumez4, F-R Pruvot2, S Truant2. 1. Digestive Surgery and Transplantation Department, CHRU of Lille, avenue Michel-Polonowski, 59037 Lille, France; University of Lille, 59000 Lille, France. Electronic address: mehdi.elamrani@chru-lille.fr. 2. Digestive Surgery and Transplantation Department, CHRU of Lille, avenue Michel-Polonowski, 59037 Lille, France; University of Lille, 59000 Lille, France. 3. University of Lille, 59000 Lille, France; Medical Information Department, CHRU of Lille, 59000 Lille, France. 4. University of Lille, 59000 Lille, France; Biostatistics Department, EA 2694, 59000 Lille, France.
Abstract
OBJECTIVE: To define the cost of pancreatectomies and to identify factors associated with increased hospital costs after pancreatic resection. METHODS: All patients undergoing pancreatic surgery in our department between January 2008 and December 2014 were included. All complications occurring during hospitalization or in the 90-day period after discharge were documented. The hospital costs were analyzed and predictive factors of increased hospital costs were determined. RESULTS: One hundred and twenty seven patients were identified. Most patients underwent pancreatectomy for malignant tumors (70%). Median hospital costs were 21,392 [15,998-29,667] euros. Age (P=0.011) and preoperative jaundice (P<0.001) were associated with higher hospital costs. Intraoperative surgical time and blood loss were correlated with increased costs (P=0.001 and P=0.002, respectively). Pancreatoduodenectomy was associated with statistically significantly higher costs compared to distal pancreatectomy (21,770 vs. 15,422 euros, P=0.001). Severe postoperative complications (Clavien-Dindo grade≥3) (P=0.001), septic complications (P=0.002) and hemorrhage (P=0.001) statistically significantly increased costs. In multivariate analysis, septic (P=0.003) and severe complications (P=0.01) were statistically significantly associated with increased hospital costs. CONCLUSION: Pancreatic surgery is associated with high hospital costs, essentially related to postoperative complications.
OBJECTIVE: To define the cost of pancreatectomies and to identify factors associated with increased hospital costs after pancreatic resection. METHODS: All patients undergoing pancreatic surgery in our department between January 2008 and December 2014 were included. All complications occurring during hospitalization or in the 90-day period after discharge were documented. The hospital costs were analyzed and predictive factors of increased hospital costs were determined. RESULTS: One hundred and twenty seven patients were identified. Most patients underwent pancreatectomy for malignant tumors (70%). Median hospital costs were 21,392 [15,998-29,667] euros. Age (P=0.011) and preoperative jaundice (P<0.001) were associated with higher hospital costs. Intraoperative surgical time and blood loss were correlated with increased costs (P=0.001 and P=0.002, respectively). Pancreatoduodenectomy was associated with statistically significantly higher costs compared to distal pancreatectomy (21,770 vs. 15,422 euros, P=0.001). Severe postoperative complications (Clavien-Dindo grade≥3) (P=0.001), septic complications (P=0.002) and hemorrhage (P=0.001) statistically significantly increased costs. In multivariate analysis, septic (P=0.003) and severe complications (P=0.01) were statistically significantly associated with increased hospital costs. CONCLUSION:Pancreatic surgery is associated with high hospital costs, essentially related to postoperative complications.
Authors: Ralph J A Linnemann; Bob J L Kooijman; Christian S van der Hilst; Joost Sprakel; Carlijn I Buis; Schelto Kruijff; Joost M Klaase Journal: Cancers (Basel) Date: 2021-12-14 Impact factor: 6.639