Literature DB >> 29705995

Using 'collective omics data' for biomedical research training.

Damien Chaussabel1, Darawan Rinchai1.   

Abstract

Systems-scale molecular profiling data accumulating in public repositories may constitute a useful resource for immunologists. It is for instance likely that information relevant to their chosen line of research be found among the more than 90,000 data series available in the NCBI Gene Expression Omnibus. Such 'collective omics data' may also be employed as source material for training purposes. This is the case when training curricula aim at the development of bioinformatics skills necessary for the analysis, interpretation or visualization of data generated on global scales. But 'collective omics data' may also be reused for training purposes to foster the development of the skills and 'mental habits' underpinning traditional reductionist science approaches. This review describes a small-scale initiative involving investigators, for the most part immunologists, having engaged in a range of training activities relying on 'collective omics data'.
© 2018 John Wiley & Sons Ltd.

Keywords:  bioinformatics; genomics; transcriptomics

Mesh:

Year:  2018        PMID: 29705995      PMCID: PMC6099165          DOI: 10.1111/imm.12944

Source DB:  PubMed          Journal:  Immunology        ISSN: 0019-2805            Impact factor:   7.397


  18 in total

1.  Differential splicing across immune system lineages.

Authors:  Ayla Ergun; Graeme Doran; James C Costello; Henry H Paik; James J Collins; Diane Mathis; Christophe Benoist
Journal:  Proc Natl Acad Sci U S A       Date:  2013-08-09       Impact factor: 11.205

2.  THE TRAINING OF NEXT GENERATION DATA SCIENTISTS IN BIOMEDICINE.

Authors:  Lana X Garmire; Stephen Gliske; Quynh C Nguyen; Jonathan H Chen; Shamim Nemati; John D VAN Horn; Jason H Moore; Carol Shreffler; Michelle Dunn
Journal:  Pac Symp Biocomput       Date:  2017

3.  RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms and GTPase binding in bipolar disorder.

Authors:  N Akula; J Barb; X Jiang; J R Wendland; K H Choi; S K Sen; L Hou; D T W Chen; G Laje; K Johnson; B K Lipska; J E Kleinman; H Corrada-Bravo; S Detera-Wadleigh; P J Munson; F J McMahon
Journal:  Mol Psychiatry       Date:  2014-01-07       Impact factor: 15.992

Review 4.  Democratizing systems immunology with modular transcriptional repertoire analyses.

Authors:  Damien Chaussabel; Nicole Baldwin
Journal:  Nat Rev Immunol       Date:  2014-04       Impact factor: 53.106

5.  A curated transcriptome dataset collection to investigate the development and differentiation of the human placenta and its associated pathologies.

Authors:  Alexandra K Marr; Sabri Boughorbel; Scott Presnell; Charlie Quinn; Damien Chaussabel; Tomoshige Kino
Journal:  F1000Res       Date:  2016-03-09

6.  A curated compendium of monocyte transcriptome datasets of relevance to human monocyte immunobiology research.

Authors:  Darawan Rinchai; Sabri Boughorbel; Scott Presnell; Charlie Quinn; Damien Chaussabel
Journal:  F1000Res       Date:  2016-04-25

7.  -A curated transcriptomic dataset collection relevant to embryonic development associated with in vitro fertilization in healthy individuals and patients with polycystic ovary syndrome.

Authors:  Rafah Mackeh; Sabri Boughorbel; Damien Chaussabel; Tomoshige Kino
Journal:  F1000Res       Date:  2017-02-23

8.  A collection of annotated and harmonized human breast cancer transcriptome datasets, including immunologic classification.

Authors:  Lance D Miller; Davide Bedognetti; Wouter Hendrickx; Jessica Roelands; Julie Decock; Sabri Boughorbel; Darawan Rinchai; Cristina Maccalli; Michele Ceccarelli; Michael Black; Cris Print; Jeff Chou; Scott Presnell; Charlie Quinn; Puthen Jithesh; Najeeb Syed; Salha B J Al Bader; Shahinaz Bedri; Ena Wang; Francesco M Marincola; Damien Chaussabel; Peter Kuppen
Journal:  F1000Res       Date:  2017-03-20

9.  A curated transcriptome dataset collection to investigate the immunobiology of HIV infection.

Authors:  Jana Blazkova; Sabri Boughorbel; Scott Presnell; Charlie Quinn; Damien Chaussabel
Journal:  F1000Res       Date:  2016-03-11

10.  Blood Interferon Signatures Putatively Link Lack of Protection Conferred by the RTS,S Recombinant Malaria Vaccine to an Antigen-specific IgE Response.

Authors:  Darawan Rinchai; Scott Presnell; Marta Vidal; Sheetij Dutta; Virander Chauhan; David Cavanagh; Gemma Moncunill; Carlota Dobaño; Damien Chaussabel
Journal:  F1000Res       Date:  2015-09-29
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  5 in total

1.  Bioinformatics for immunologists.

Authors:  Daniel M Altmann
Journal:  Immunology       Date:  2018-09       Impact factor: 7.397

2.  A curated collection of transcriptome datasets to investigate the molecular mechanisms of immunoglobulin E-mediated atopic diseases.

Authors:  Susie S Y Huang; Fatima Al Ali; Sabri Boughorbel; Mohammed Toufiq; Damien Chaussabel; Mathieu Garand
Journal:  Database (Oxford)       Date:  2019-01-01       Impact factor: 3.451

Review 3.  Long-Chain Acyl-CoA Synthetase 1 Role in Sepsis and Immunity: Perspectives From a Parallel Review of Public Transcriptome Datasets and of the Literature.

Authors:  Jessica Roelands; Mathieu Garand; Emily Hinchcliff; Ying Ma; Parin Shah; Mohammed Toufiq; Mohamed Alfaki; Wouter Hendrickx; Sabri Boughorbel; Darawan Rinchai; Amir Jazaeri; Davide Bedognetti; Damien Chaussabel
Journal:  Front Immunol       Date:  2019-10-18       Impact factor: 7.561

Review 4.  Annexin A3 in sepsis: novel perspectives from an exploration of public transcriptome data.

Authors:  Mohammed Toufiq; Jessica Roelands; Mohamed Alfaki; Basirudeen Syed Ahamed Kabeer; Marwa Saadaoui; Arun Prasath Lakshmanan; Dhinoth Kumar Bangarusamy; Selvasankar Murugesan; Davide Bedognetti; Wouter Hendrickx; Souhaila Al Khodor; Annalisa Terranegra; Darawan Rinchai; Damien Chaussabel; Mathieu Garand
Journal:  Immunology       Date:  2020-08-31       Impact factor: 7.397

5.  Connection of BANK1, Tolerance, Regulatory B cells, and Apoptosis: Perspectives of a Reductionist Investigation.

Authors:  Ludmilla Le Berre; Mélanie Chesneau; Richard Danger; Florian Dubois; Damien Chaussabel; Mathieu Garand; Sophie Brouard
Journal:  Front Immunol       Date:  2021-03-18       Impact factor: 7.561

  5 in total

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