Zhennan Zhao1, Wen Wen1, Chunhui Jiang2, Yi Lu3. 1. From the Department of Ophthalmology and Vision Science (Zhao, Wen, Jiang, Lu), Eye and Ear, Nose, and Throat Hospital, Fudan University, Key Laboratory of Myopia of State Health Ministry and Key Laboratory of Visual Impairment and Restoration of Shanghai (Zhao, Wen, Jiang, Lu), and the Department of Ophthalmology (Jiang), Number 5 People's Hospital of Shanghai, Shanghai, China. 2. From the Department of Ophthalmology and Vision Science (Zhao, Wen, Jiang, Lu), Eye and Ear, Nose, and Throat Hospital, Fudan University, Key Laboratory of Myopia of State Health Ministry and Key Laboratory of Visual Impairment and Restoration of Shanghai (Zhao, Wen, Jiang, Lu), and the Department of Ophthalmology (Jiang), Number 5 People's Hospital of Shanghai, Shanghai, China. Electronic address: chhjiang70@163.com. 3. From the Department of Ophthalmology and Vision Science (Zhao, Wen, Jiang, Lu), Eye and Ear, Nose, and Throat Hospital, Fudan University, Key Laboratory of Myopia of State Health Ministry and Key Laboratory of Visual Impairment and Restoration of Shanghai (Zhao, Wen, Jiang, Lu), and the Department of Ophthalmology (Jiang), Number 5 People's Hospital of Shanghai, Shanghai, China. Electronic address: luyieent@126.com.
Abstract
PURPOSE: To use optical coherence tomography (OCT) angiography and a split-spectrum amplitude-decorrelation angiography algorithm to evaluate the changes in the macular vascular system after uncomplicated phacoemulsification. SETTING: Department of Ophthalmology, Eye and and Ear, Nose, and Throat Hospital of Fudan University, Shanghai, China. DESIGN: Prospective case series. METHODS: Patients with senile cataracts were included. Retinal vessel density and thickness at the macular area were checked by OCT at baseline and at 1 week, 1 month, and 3 months after cataract surgery. RESULTS: Thirty-two eyes (32 patients) were included in the final analysis. There was a significant increase in retinal vessel density, a decrease in the foveal avascular zone at the macular area after the cataract surgery (all P < .05, repeated-measures analysis of variance), and an increase in full and inner macular thickness, all of which extended to the end of the follow-up period. At 3 months postoperatively, there was a mean 6% and 3% increase in vessel density at the parafoveal and perifoveal regions, respectively, and a mean 27% reduction in the foveal avascular zone. The mean increase in inner retinal thickness was 15%, 10%, and 7% at the fovea, parafovea, and perifovea, respectively. Compared with the parafovea and perifovea, the fovea had a much higher percentage of change in retinal vasculature and inner retinal thickness (all P < .001). CONCLUSIONS: Macular vessel density and thickness increased after cataract surgery. Whether these changes will persist over a longer period still needs to be studied.
PURPOSE: To use optical coherence tomography (OCT) angiography and a split-spectrum amplitude-decorrelation angiography algorithm to evaluate the changes in the macular vascular system after uncomplicated phacoemulsification. SETTING: Department of Ophthalmology, Eye and and Ear, Nose, and Throat Hospital of Fudan University, Shanghai, China. DESIGN: Prospective case series. METHODS:Patients with senile cataracts were included. Retinal vessel density and thickness at the macular area were checked by OCT at baseline and at 1 week, 1 month, and 3 months after cataract surgery. RESULTS: Thirty-two eyes (32 patients) were included in the final analysis. There was a significant increase in retinal vessel density, a decrease in the foveal avascular zone at the macular area after the cataract surgery (all P < .05, repeated-measures analysis of variance), and an increase in full and inner macular thickness, all of which extended to the end of the follow-up period. At 3 months postoperatively, there was a mean 6% and 3% increase in vessel density at the parafoveal and perifoveal regions, respectively, and a mean 27% reduction in the foveal avascular zone. The mean increase in inner retinal thickness was 15%, 10%, and 7% at the fovea, parafovea, and perifovea, respectively. Compared with the parafovea and perifovea, the fovea had a much higher percentage of change in retinal vasculature and inner retinal thickness (all P < .001). CONCLUSIONS: Macular vessel density and thickness increased after cataract surgery. Whether these changes will persist over a longer period still needs to be studied.
Authors: Tun Wang Ch'ng; Kevin Gillmann; Kirsten Hoskens; Harsha L Rao; André Mermoud; Kaweh Mansouri Journal: Eye (Lond) Date: 2019-08-13 Impact factor: 3.775