| Literature DB >> 29704884 |
Akemi Ishida-Yamamoto1, Satomi Igawa1, Mari Kishibe1.
Abstract
The barrier function of skin is indispensable for terrestrial animals. This function is mainly carried out by the epidermis, more specifically by its granular and cornified layers. The major structural components associated with this function are the intercellular lipid layer, desmosomes, corneodesmosomes, tight junctions, cornified cell envelope and keratin filaments. In this review, we discuss the current knowledge of their ultrastructure, their molecular basis and their relevance to skin disease.Entities:
Keywords: corneodesmosome; cornified cell envelope; keratohyalin granules; lamellar granules; tight junctions
Mesh:
Substances:
Year: 2018 PMID: 29704884 DOI: 10.1111/exd.13674
Source DB: PubMed Journal: Exp Dermatol ISSN: 0906-6705 Impact factor: 3.960